C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade A, member 1A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000066366 Serpina1a 10090 - 12:103853589-103863562 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072876 Serpina1a-001 103853589-103863555 protein_coding
  ENSMUST00000085056 Serpina1a-002 103853591-103863551 protein_coding
  ENSMUST00000124717 Serpina1a-003 103857764-103863562 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072876ENSMUST00000085056ENSMUST00000124717
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072876 0.784±0.45 N/A 0.045±0.02 N/A 0.298±0.00 N/A N/A N/A N/A N/A N/A 0.093±0.00 N/A 0.104±0.04
ENSMUST00000085056 0.229±0.10 0.635±0.49 0.053±0.00 0.054±0.00 3.824±3.33 0.072±0.02 0.244±0.00 2.480±0.76 333.087±83.19 0.347±0.14 0.038±0.00 1.258±0.90 28.064±34.43 0.271±0.18
ENSMUST00000124717 N/A 0.135±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000598 CIL_000598_000S CGP 12:103763594-103863562
CIL_000598 CIL_000598_000R CGP 12:103853589-103904887

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005615 IEA extracellular space
GO:0006487 IDA protein N-linked glycosylation
GO:0006953 IEA acute-phase response
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0034097 IDA response to cytokine
GO:0043434 IDA response to peptide hormone

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074712 si:ch211-186e20.2 si:ch211-186e20.2 protein_coding Danio_rerio
ENSDARG00000077960 si:ch211-186e20.7 si:ch211-186e20.7 protein_coding Danio_rerio
ENSDARG00000087143 serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 protein_coding Danio_rerio
ENSDARG00000090286 serpina1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Danio_rerio
ENSDARG00000090850 serpina1l serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like protein_coding Danio_rerio
ENSDARG00000090916 CR559930.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000091136 zgc:174259 zgc:174259 protein_coding Danio_rerio
ENSDARG00000091800 zgc:174260 zgc:174260 protein_coding Danio_rerio
ENSG00000197249 SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Homo_sapiens

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