C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CD59b antigen
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068686 Cd59b 10090 + 2:104069849-104091187 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090429 Cd59b-201 104071010-104084957 protein_coding
  ENSMUST00000111130 Cd59b-202 104071066-104084820 protein_coding
  ENSMUST00000111131 Cd59b-001 104069849-104091160 protein_coding
  ENSMUST00000111132 Cd59b-002 104069849-104091187 protein_coding
  ENSMUST00000129749 Cd59b-003 104069891-104084645 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000090429ENSMUST00000111130ENSMUST00000111131ENSMUST00000111132ENSMUST00000129749
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000090429 N/A N/A N/A 0.091±0.02 N/A N/A N/A N/A 1.040±0.18 N/A 0.556±0.01 0.591±0.16 0.587±0.08 1.808±1.03
ENSMUST00000111130 N/A N/A N/A N/A N/A N/A N/A N/A 0.611±0.00 N/A N/A 0.590±0.00 N/A 6.998±1.90
ENSMUST00000111131 4.814±1.87 2.684±1.33 3.558±0.07 0.659±0.54 5.419±3.75 0.277±0.07 2.139±0.44 5.895±1.23 3.071±1.73 1.472±0.33 0.789±0.13 1.442±0.87 2.775±1.34 N/A
ENSMUST00000111132 5.193±1.65 8.490±1.34 6.011±0.62 0.718±0.12 6.815±4.18 1.180±0.27 3.970±1.35 7.922±1.93 10.282±5.46 1.931±0.80 6.355±1.59 3.331±1.80 2.946±1.17 5.703±0.74
ENSMUST00000129749 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.603±0.10 1.877±0.94 9.803±8.72

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000929 CIL_000929_0002 VISTA 2:103593010-104195664

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001775 IBA cell activation
GO:0001848 IBA complement binding
GO:0001971 IDA negative regulation of activation of membrane attack complex
GO:0005576 IBA extracellular region
GO:0005886 IBA plasma membrane
GO:0007166 IBA cell surface receptor signaling pathway
GO:0009986 IDA cell surface
GO:0031225 IEA anchored component of membrane
GO:0045916 IDA negative regulation of complement activation
GO:0045918 IDA negative regulation of cytolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000085063 CD59 CD59 molecule, complement regulatory protein protein_coding Homo_sapiens

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