C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth differentiation factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000072625 Gdf2 10090 + 14:33941039-33947198 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000100720 Gdf2-201 33941039-33947198 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartLiverLungOvaryPlacentaTestisENSMUST00000100720
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Liver Lung Ovary Placenta Testis
ENSMUST00000100720 0.025±0.01 0.036±0.01 0.005±0.00 0.011±0.01 0.034±0.00 0.067±0.02 3.113±0.98 0.209±0.04 0.038±0.02 0.085±0.08 0.010±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006FX CIL_0006FX_0003 CGP 14:33923587-33947198
CIL_0006P7 CIL_0006P7_0003 CGP 14:33941039-33964216

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0001569 IDA patterning of blood vessels
GO:0001570 IDA vasculogenesis
GO:0001649 IGI osteoblast differentiation
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0006006 TAS glucose metabolic process
GO:0006879 TAS cellular iron ion homeostasis
GO:0008083 IEA growth factor activity
GO:0010596 IEA negative regulation of endothelial cell migration
GO:0010628 IDA positive regulation of gene expression
GO:0010862 IEA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030182 TAS neuron differentiation
GO:0030308 IEA negative regulation of cell growth
GO:0030509 IEA BMP signaling pathway
GO:0030513 IDA positive regulation of BMP signaling pathway
GO:0032757 IEA positive regulation of interleukin-8 production
GO:0032924 IEA activin receptor signaling pathway
GO:0040007 IEA growth
GO:0045603 IDA positive regulation of endothelial cell differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045766 IDA positive regulation of angiogenesis
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048514 IEA blood vessel morphogenesis
GO:0060389 IEA pathway-restricted SMAD protein phosphorylation
GO:0070062 IEA extracellular vesicular exosome
GO:0071773 IEA cellular response to BMP stimulus
GO:2000279 IEA negative regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059173 gdf2 growth differentiation factor 2 protein_coding Danio_rerio
ENSG00000263761 GDF2 growth differentiation factor 2 protein_coding Homo_sapiens

Loading