C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000074886 Grk6 10090 + 13:55445334-55460925 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001115 Grk6-201 55445334-55460925 protein_coding
  ENSMUST00000099482 Grk6-202 55445334-55459577 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001115ENSMUST00000099482
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001115 27.318±1.78 22.446±4.03 16.197±3.24 13.528±7.33 39.887±6.90 24.981±4.92 6.833±1.40 8.356±1.95 12.444±8.01 21.004±0.80 2.723±1.45 20.476±6.12 6.104±3.27 2.254±0.76
ENSMUST00000099482 N/A N/A N/A 9.893±5.63 N/A N/A N/A N/A N/A N/A 1.523±0.00 12.554±0.00 4.706±1.32 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0002 VISTA 13:55104361-55707564
CIL_0002YH CIL_0002YH_0002 CGP 13:55417958-55460925
CIL_0000XA CIL_0000XA_0003 CGP 13:55445334-55473155

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0016020 IEA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032157 GRK6 Uncharacterized protein protein_coding Danio_rerio
ENSG00000198055 GRK6 G protein-coupled receptor kinase 6 protein_coding Homo_sapiens

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