C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement factor B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000090231 Cfb 10090 - 17:34856374-34862518 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025229 Cfb-201 34856384-34862514 protein_coding
  ENSMUST00000128767 Cfb-001 34856374-34862518 protein_coding
  ENSMUST00000133127 Cfb-003 34856574-34859041 nonsense_mediated_decay
  ENSMUST00000141295 Cfb-005 34856374-34859025 protein_coding
  ENSMUST00000153400 Cfb-004 34856391-34858142 protein_coding
  ENSMUST00000154526 Cfb-002 34856379-34862173 protein_coding
  ENSMUST00000176203 Cfb-202 34856384-34862514 protein_coding
  ENSMUST00000176332 Cfb-006 34856412-34859310 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000025229ENSMUST00000128767ENSMUST00000154526
Transcript ID Adipose Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000025229 33.827±18.84 10.501±2.23 18.353±4.26 10.776±2.67 1.961±0.17 60.326±11.07 155.512±83.91 10.032±1.16 1.459±0.88 8.738±1.77 21.269±15.76
ENSMUST00000128767 12.471±4.32 6.440±0.00 11.653±0.00 9.405±1.91 0.912±0.00 14.240±0.47 97.524±65.79 5.688±0.65 N/A 8.197±0.00 20.292±19.42
ENSMUST00000154526 29.315±11.57 N/A 19.615±3.83 6.846±2.01 N/A 25.490±6.40 106.503±52.07 5.027±0.00 1.156±0.20 11.792±5.13 2.205±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PM CIL_0001PM_0004 CGP 17:34856374-34882042

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IEA serine-type endopeptidase activity
GO:0005576 IEA extracellular region
GO:0006508 IEA proteolysis
GO:0006957 TAS complement activation, alternative pathway
GO:0008283 TAS cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005616 bfb complement component bfb protein_coding Danio_rerio
ENSDARG00000055278 cfb complement factor B protein_coding Danio_rerio
ENSDARG00000090730 zgc:158446 zgc:158446 protein_coding Danio_rerio
ENSG00000243649 CFB complement factor B protein_coding Homo_sapiens
ENSG00000244255 CFB Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000410815}; cDNA FLJ55673, highly similar to Complement factor B {ECO:000031 protein_coding Homo_sapiens

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