C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sclerostin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000001534 Sost-001 ENSMUSG00000001494 10090 - 11:101962458-101967015 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001534
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001534 0.075±0.05 0.161±0.03 0.009±0.00 0.088±0.01 0.087±0.08 0.063±0.00 2.941±0.69 1.015±0.18 0.069±0.04 0.986±0.06 0.028±0.01 0.107±0.04 0.052±0.02 1.517±0.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000996 CIL_000996_0002 VISTA 11:101501412-102102123
CIL_00090X CIL_00090X_0002 VISTA 11:101529827-102131014
CIL_000997 CIL_000997_0002 VISTA 11:101567301-102168287
CIL_00059O CIL_00059O_0002 CGP 11:101877510-101967015
CIL_0001CB CIL_0001CB_0002 CGP 11:101962458-101987013

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IDA ossification
GO:0005515 IPI protein binding
GO:0005794 IEA Golgi apparatus
GO:0008134 IEA transcription factor binding
GO:0009612 IEA response to mechanical stimulus
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030279 IMP negative regulation of ossification
GO:0030514 ISA negative regulation of BMP signaling pathway
GO:0031012 IEA extracellular matrix
GO:0031333 IEA negative regulation of protein complex assembly
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0071374 IEA cellular response to parathyroid hormone stimulus
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:2000054 IEA negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000301691 SOST-001 protein_coding Homo_sapiens 0 771

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