C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP dependent, catalytic, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000005606 Prkaca-201 ENSMUSG00000005469 10090 + 8:83972978-83996445 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005606
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005606 82.184±18.18 62.917±14.91 33.922±4.40 40.736±8.72 57.989±4.98 36.736±5.63 99.112±10.26 42.397±1.01 23.517±5.05 35.711±2.88 47.647±3.21 43.071±9.53 18.428±7.58 14.712±6.09

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001707 IGI mesoderm formation
GO:0001843 IGI neural tube closure
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004691 IDA cAMP-dependent protein kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005813 IEA centrosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0016020 IEA membrane
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0031588 IEA AMP-activated protein kinase complex
GO:0031594 IDA neuromuscular junction
GO:0031625 IEA ubiquitin protein ligase binding
GO:0034237 IEA protein kinase A regulatory subunit binding
GO:0045667 IEA regulation of osteoblast differentiation
GO:0046777 IDA protein autophosphorylation
GO:0046827 IMP positive regulation of protein export from nucleus
GO:0048240 IDA sperm capacitation
GO:0050804 IMP regulation of synaptic transmission
GO:0061136 IEA regulation of proteasomal protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0070613 IGI regulation of protein processing
GO:0071158 IDA positive regulation of cell cycle arrest
GO:0071333 IEA cellular response to glucose stimulus
GO:0071374 IMP cellular response to parathyroid hormone stimulus
GO:0097225 ISS sperm midpiece
GO:0097546 IDA ciliary base
GO:1901621 IGI negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000810 IEA regulation of tight junction assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000308677 PRKACA-001 protein_coding Homo_sapiens 0 1836
ENST00000350356 PRKACA-005 processed_transcript Homo_sapiens 0 1495
ENST00000377276 PRKACG-001 protein_coding Homo_sapiens 0 1158
ENST00000536649 PRKACA-004 retained_intron Homo_sapiens 0 907
ENST00000587372 PRKACA-010 protein_coding Homo_sapiens 0 813
ENST00000587533 PRKACA-007 retained_intron Homo_sapiens 0 198
ENST00000588209 PRKACA-009 retained_intron Homo_sapiens 0 789
ENST00000589994 PRKACA-003 protein_coding Homo_sapiens 0 1387
ENST00000590853 PRKACA-002 protein_coding Homo_sapiens 0 390
ENST00000593092 PRKACA-006 protein_coding Homo_sapiens 0 739

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