C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tissue inhibitor of metalloproteinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000017610 Timp2-001 ENSMUSG00000017466 10090 - 11:118301069-118355506 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017610
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017610 132.172±30.13 53.835±15.19 281.181±12.74 31.687±9.54 124.623±55.34 58.419±1.03 31.519±3.99 37.086±1.97 3.597±0.82 202.115±4.43 16.942±1.20 117.175±40.47 13.508±10.13 25.142±10.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003UE CIL_0003UE_0003 CGP 11:118259651-118355740
CIL_00062J CIL_00062J_0002 CGP 11:118301069-118355740

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005178 IDA integrin binding
GO:0005604 IDA basement membrane
GO:0005615 IEA extracellular space
GO:0007417 IEA central nervous system development
GO:0007568 IEA aging
GO:0008047 IMP enzyme activator activity
GO:0008191 TAS metalloendopeptidase inhibitor activity
GO:0008285 IDA negative regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030426 IEA growth cone
GO:0030814 IDA regulation of cAMP metabolic process
GO:0032487 IEA regulation of Rap protein signal transduction
GO:0034097 IEA response to cytokine
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043408 IDA regulation of MAPK cascade
GO:0043410 IEA positive regulation of MAPK cascade
GO:0045664 IDA regulation of neuron differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045762 IEA positive regulation of adenylate cyclase activity
GO:0045861 IEA negative regulation of proteolysis
GO:0045930 IEA negative regulation of mitotic cell cycle
GO:0046580 IEA negative regulation of Ras protein signal transduction
GO:0070062 IEA extracellular vesicular exosome
GO:0071310 IDA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262768 TIMP2-001 protein_coding Homo_sapiens 0 1240
ENST00000536189 TIMP2-003 protein_coding Homo_sapiens 0 1016
ENST00000585421 TIMP2-008 protein_coding Homo_sapiens 0 1013
ENST00000586057 TIMP2-004 protein_coding Homo_sapiens 0 1016
ENST00000586713 KIAA1731NL-004 protein_coding Homo_sapiens 0 255
ENST00000592761 TIMP2-002 nonsense_mediated_decay Homo_sapiens 0 446

Loading