C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: regulator of cell cycle
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022595 Rgcc-001 ENSMUSG00000022018 10090 - 14:79288756-79301645 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022595
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022595 255.576±175.49 302.232±77.30 8.255±2.59 15.820±8.11 114.511±42.74 41.612±5.54 37.195±11.57 37.624±12.51 37.663±46.44 85.375±48.36 26.017±5.46 103.578±52.65 51.665±31.51 7.219±1.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 ISO G1/S transition of mitotic cell cycle
GO:0001100 IEA negative regulation of exit from mitosis
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0003331 IEA positive regulation of extracellular matrix constituent secretion
GO:0005515 IPI protein binding
GO:0005634 ISO nucleus
GO:0005737 ISO cytoplasm
GO:0005813 IEA centrosome
GO:0006956 IEA complement activation
GO:0008285 IEA negative regulation of cell proliferation
GO:0010628 IEA positive regulation of gene expression
GO:0010718 IEA positive regulation of epithelial to mesenchymal transition
GO:0016525 IEA negative regulation of angiogenesis
GO:0019901 IEA protein kinase binding
GO:0030295 ISO protein kinase activator activity
GO:0031659 IEA positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0043537 IEA negative regulation of blood vessel endothelial cell migration
GO:0045840 IEA positive regulation of mitosis
GO:0050710 IEA negative regulation of cytokine secretion
GO:0050715 IEA positive regulation of cytokine secretion
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0070412 IEA R-SMAD binding
GO:0071158 IEA positive regulation of cell cycle arrest
GO:0071456 IEA cellular response to hypoxia
GO:0071850 IEA mitotic cell cycle arrest
GO:0072537 IMP fibroblast activation
GO:0090272 IEA negative regulation of fibroblast growth factor production
GO:1901313 IEA positive regulation of gene expression involved in extracellular matrix organization
GO:1901991 IEA negative regulation of mitotic cell cycle phase transition
GO:2000048 IEA negative regulation of cell-cell adhesion mediated by cadherin
GO:2000353 IEA positive regulation of endothelial cell apoptotic process
GO:2000573 IEA positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000379359 RGCC-001 protein_coding Homo_sapiens 0 658

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