C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hematopoietically expressed homeobox
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025944 Hhex-001 ENSMUSG00000024986 10090 + 19:37434810-37440731 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025944
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025944 3.180±0.88 148.191±80.32 2.166±0.20 0.786±0.20 19.531±11.45 2.521±0.95 0.991±0.38 1.739±0.46 29.453±20.39 13.352±2.74 0.509±0.29 6.365±3.59 0.894±0.39 0.446±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VX CIL_0007VX_0002 VISTA 19:37192022-37797349
CIL_00018T CIL_00018T_0002 CGP 19:37376403-37440731
CIL_0000ZV CIL_0000ZV_0002 CGP 19:37434810-37683245

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001570 IMP vasculogenesis
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0002009 IMP morphogenesis of an epithelium
GO:0002573 IMP myeloid leukocyte differentiation
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006406 IEA mRNA export from nucleus
GO:0007165 IMP signal transduction
GO:0007492 IMP endoderm development
GO:0008134 IEA transcription factor binding
GO:0008190 IEA eukaryotic initiation factor 4E binding
GO:0008283 IEA cell proliferation
GO:0008301 IEA DNA binding, bending
GO:0009611 IEA response to wounding
GO:0009887 IMP organ morphogenesis
GO:0009952 IMP anterior/posterior pattern specification
GO:0016055 IEA Wnt signaling pathway
GO:0016525 IDA negative regulation of angiogenesis
GO:0016973 IEA poly(A)+ mRNA export from nucleus
GO:0022027 IMP interkinetic nuclear migration
GO:0030097 IMP hemopoiesis
GO:0030154 IEA cell differentiation
GO:0030177 IMP positive regulation of Wnt signaling pathway
GO:0030183 IMP B cell differentiation
GO:0030878 IMP thyroid gland development
GO:0030900 IMP forebrain development
GO:0030948 IDA negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031016 IMP pancreas development
GO:0032993 IEA protein-DNA complex
GO:0034504 IEA protein localization to nucleus
GO:0035050 IMP embryonic heart tube development
GO:0035264 IMP multicellular organism growth
GO:0042127 IMP regulation of cell proliferation
GO:0042803 IEA protein homodimerization activity
GO:0043434 IEA response to peptide hormone
GO:0043565 ISS sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045736 IEA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048568 IMP embryonic organ development
GO:0048729 IMP tissue morphogenesis
GO:0048853 IMP forebrain morphogenesis
GO:0060431 IMP primary lung bud formation
GO:0061009 IMP common bile duct development
GO:0061010 IMP gall bladder development
GO:0061011 IMP hepatic duct development
GO:0061017 IMP hepatoblast differentiation
GO:0070365 IMP hepatocyte differentiation
GO:0070491 IEA repressing transcription factor binding
GO:0071103 IEA DNA conformation change
GO:0071837 IPI HMG box domain binding
GO:0090009 IGI primitive streak formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000282728 HHEX-001 protein_coding Homo_sapiens 0 1027
ENST00000472590 HHEX-002 protein_coding Homo_sapiens 0 531
ENST00000492654 HHEX-003 protein_coding Homo_sapiens 0 510
ENST00000551454 HHEX-004 retained_intron Homo_sapiens 0 499

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