C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 40 (iron-regulated transporter), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000027137 Slc40a1-001 ENSMUSG00000025993 10090 - 1:45908068-45925582 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027137
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027137 6.618±3.94 2.322±0.27 5.279±0.07 3.735±1.46 2.772±0.83 27.429±2.93 4.334±0.64 19.128±0.96 37.817±9.68 3.666±1.18 7.125±1.08 12.054±2.90 40.623±21.41 0.341±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002260 IMP lymphocyte homeostasis
GO:0003158 IMP endothelium development
GO:0005381 IDA iron ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005771 IDA multivesicular body
GO:0005886 IDA plasma membrane
GO:0006826 IDA iron ion transport
GO:0006879 IGI cellular iron ion homeostasis
GO:0008021 IDA synaptic vesicle
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0034395 IDA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0034755 IDA iron ion transmembrane transport
GO:0043066 IMP negative regulation of apoptotic process
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IMP spleen development
GO:0060345 IMP spleen trabecula formation
GO:0060586 IMP multicellular organismal iron ion homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261024 SLC40A1-001 protein_coding Homo_sapiens 0 2206
ENST00000418714 SLC40A1-008 processed_transcript Homo_sapiens 0 285
ENST00000479598 SLC40A1-006 retained_intron Homo_sapiens 0 640

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