C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transforming growth factor alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032066 Tgfa-201 ENSMUSG00000029999 10090 + 6:86195251-86275449 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032066
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032066 1.306±1.09 8.596±0.23 2.480±0.45 2.832±0.61 1.726±0.13 8.324±0.76 0.345±0.08 1.654±0.12 2.411±1.38 4.908±0.13 0.123±0.09 8.885±2.87 2.541±0.98 1.140±0.49

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089T CIL_00089T_0002 VISTA 6:86179085-86780169

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 ISS activation of MAPK activity
GO:0001525 IDA angiogenesis
GO:0001948 IDA glycoprotein binding
GO:0005154 ISS epidermal growth factor receptor binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0008083 ISS growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0045741 ISS positive regulation of epidermal growth factor-activated receptor activity
GO:0045840 ISS positive regulation of mitosis
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048523 IEA negative regulation of cellular process
GO:0050679 ISS positive regulation of epithelial cell proliferation
GO:0051781 IEA positive regulation of cell division
GO:0060749 IGI mammary gland alveolus development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000295400 TGFA-001 protein_coding Homo_sapiens 0 625
ENST00000418333 TGFA-016 protein_coding Homo_sapiens 0 640
ENST00000419940 TGFA-006 protein_coding Homo_sapiens 0 479
ENST00000444975 TGFA-002 protein_coding Homo_sapiens 0 592
ENST00000445399 TGFA-005 protein_coding Homo_sapiens 0 568
ENST00000450929 TGFA-003 protein_coding Homo_sapiens 0 606

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