C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: toll-like receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034056 Tlr3-201 ENSMUSG00000031639 10090 - 8:45395665-45410539 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034056
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034056 1.600±0.50 0.329±0.00 1.545±0.06 0.199±0.04 1.361±0.44 1.274±0.80 0.738±0.19 0.813±0.22 0.373±0.19 2.260±0.35 0.178±0.05 1.223±0.39 0.428±0.24 0.146±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001774 IEA microglial cell activation
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002224 IEA toll-like receptor signaling pathway
GO:0002282 IEA microglial cell activation involved in immune response
GO:0002756 IEA MyD88-independent toll-like receptor signaling pathway
GO:0003725 ISS double-stranded RNA binding
GO:0004872 IEA receptor activity
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005765 IEA lysosomal membrane
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0006952 IMP defense response
GO:0006954 IEA inflammatory response
GO:0007252 IEA I-kappaB phosphorylation
GO:0008584 IEA male gonad development
GO:0009615 IMP response to virus
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0032481 IDA positive regulation of type I interferon production
GO:0032722 IEA positive regulation of chemokine production
GO:0032728 IDA positive regulation of interferon-beta production
GO:0032735 IDA positive regulation of interleukin-12 production
GO:0032755 IDA positive regulation of interleukin-6 production
GO:0032757 IEA positive regulation of interleukin-8 production
GO:0032760 IDA positive regulation of tumor necrosis factor production
GO:0034123 IEA positive regulation of toll-like receptor signaling pathway
GO:0034138 IEA toll-like receptor 3 signaling pathway
GO:0034346 IDA positive regulation of type III interferon production
GO:0035458 IEA cellular response to interferon-beta
GO:0035690 IEA cellular response to drug
GO:0042346 IEA positive regulation of NF-kappaB import into nucleus
GO:0043065 IEA positive regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 IMP response to exogenous dsRNA
GO:0043331 IEA response to dsRNA
GO:0045078 ISS positive regulation of interferon-gamma biosynthetic process
GO:0045080 IMP positive regulation of chemokine biosynthetic process
GO:0045087 TAS innate immune response
GO:0045356 ISS positive regulation of interferon-alpha biosynthetic process
GO:0045359 ISS positive regulation of interferon-beta biosynthetic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IDA positive regulation of JNK cascade
GO:0050729 IEA positive regulation of inflammatory response
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051607 TAS defense response to virus
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071346 IEA cellular response to interferon-gamma
GO:0071359 IEA cellular response to dsRNA
GO:0071360 IEA cellular response to exogenous dsRNA
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097527 IEA necroptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000296795 TLR3-001 protein_coding Homo_sapiens 0 2274
ENST00000504367 TLR3-003 protein_coding Homo_sapiens 0 1844
ENST00000512264 TLR3-004 retained_intron Homo_sapiens 0 1840

Loading