C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: macrophage migration inhibitory factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000038169 Mif-201 ENSMUSG00000033307 10090 - 10:75859353-75860250 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038169
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038169 216.331±105.69 470.478±31.34 259.093±26.45 581.488±360.12 240.891±106.45 237.599±21.29 129.695±49.85 1092.330±95.73 583.312±240.62 131.663±11.58 61.759±3.87 619.933±265.89 344.055±221.32 71.536±22.87

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001516 IEA prostaglandin biosynthetic process
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0002821 NAS positive regulation of adaptive immune response
GO:0002906 IDA negative regulation of mature B cell apoptotic process
GO:0004167 ISS dopachrome isomerase activity
GO:0005102 IEA receptor binding
GO:0005125 IDA cytokine activity
GO:0005126 IEA cytokine receptor binding
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0006954 IEA inflammatory response
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007569 IMP cell aging
GO:0008283 IEA cell proliferation
GO:0009986 IEA cell surface
GO:0010629 IEA negative regulation of gene expression
GO:0010739 IEA positive regulation of protein kinase A signaling
GO:0019752 IEA carboxylic acid metabolic process
GO:0030330 IMP DNA damage response, signal transduction by p53 class mediator
GO:0030890 IEA positive regulation of B cell proliferation
GO:0031666 IMP positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0031982 IEA vesicle
GO:0032269 IDA negative regulation of cellular protein metabolic process
GO:0033033 IMP negative regulation of myeloid cell apoptotic process
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0042056 IEA chemoattractant activity
GO:0042127 IMP regulation of cell proliferation
GO:0042327 IEA positive regulation of phosphorylation
GO:0043066 IDA negative regulation of apoptotic process
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0043518 IDA negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045087 IEA innate immune response
GO:0048146 IDA positive regulation of fibroblast proliferation
GO:0050178 IMP phenylpyruvate tautomerase activity
GO:0050715 IEA positive regulation of cytokine secretion
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 IEA positive chemotaxis
GO:0061078 IMP positive regulation of prostaglandin secretion involved in immune response
GO:0061081 IMP positive regulation of myeloid leukocyte cytokine production involved in immune response
GO:0070062 IEA extracellular vesicular exosome
GO:0070207 IEA protein homotrimerization
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0071157 IEA negative regulation of cell cycle arrest
GO:0090238 IDA positive regulation of arachidonic acid secretion
GO:0090344 IEA negative regulation of cell aging
GO:1902166 IEA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000343 IDA positive regulation of chemokine (C-X-C motif) ligand 2 production

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000215754 MIF-001 protein_coding Homo_sapiens 0 431
ENST00000433835 AP000350.10-005 protein_coding Homo_sapiens 0 292
ENST00000465752 MIF-002 retained_intron Homo_sapiens 0 344
ENST00000498385 MIF-003 retained_intron Homo_sapiens 0 292
ENST00000613839 MIF-201 protein_coding Homo_sapiens 0 431

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