C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: epithelial mitogen
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000041516 Epgn-001 ENSMUSG00000035020 10090 + 5:91027464-91035215 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000041516
Transcript ID Adipose Bladder Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041516 0.043±0.02 0.049±0.00 0.126±0.09 0.067±0.00 0.027±0.01 0.023±0.01 0.035±0.00 0.053±0.03 0.081±0.08 0.037±0.03 0.121±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SN CIL_0006SN_0002 CGP 5:90931196-91035215
CIL_0006SO CIL_0006SO_0002 CGP 5:91027464-91093649

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0000187 IDA activation of MAPK activity
GO:0001525 ISS angiogenesis
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005887 ISS integral component of plasma membrane
GO:0008083 IDA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0043406 ISS positive regulation of MAP kinase activity
GO:0045741 IDA positive regulation of epidermal growth factor-activated receptor activity
GO:0045840 IDA positive regulation of mitosis
GO:0050679 IDA positive regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000332112 EPGN-003 protein_coding Homo_sapiens 0 272
ENST00000413830 EPGN-001 protein_coding Homo_sapiens 0 399
ENST00000446430 EPGN-009 protein_coding Homo_sapiens 0 302

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