C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: bone morphogenetic protein receptor, type 1A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000049005 Bmpr1a-001 ENSMUSG00000021796 10090 - 14:34410734-34502687 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049005
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049005 8.952±2.92 2.128±0.17 23.134±1.58 6.689±4.18 5.612±1.75 4.211±1.74 9.008±1.59 6.012±0.60 2.983±0.52 8.678±2.47 9.349±1.76 7.021±5.28 9.554±5.22 1.595±0.73

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007BV CIL_0007BV_0002 CGP 14:34375504-34503341

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001701 IMP in utero embryonic development
GO:0001707 IMP mesoderm formation
GO:0001756 IMP somitogenesis
GO:0001880 IMP Mullerian duct regression
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0003007 IMP heart morphogenesis
GO:0003272 IMP endocardial cushion formation
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0005901 IEA caveola
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006955 IEA immune response
GO:0007389 IMP pattern specification process
GO:0007398 IMP ectoderm development
GO:0007399 IMP nervous system development
GO:0007492 IMP endoderm development
GO:0007507 IMP heart development
GO:0009950 IMP dorsal/ventral axis specification
GO:0009952 IMP anterior/posterior pattern specification
GO:0009953 IGI dorsal/ventral pattern formation
GO:0010862 IEA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0014032 IMP neural crest cell development
GO:0016021 IEA integral component of membrane
GO:0019827 IMP stem cell maintenance
GO:0021983 IMP pituitary gland development
GO:0021998 IMP neural plate mediolateral regionalization
GO:0023014 IEA signal transduction by phosphorylation
GO:0030154 IGI cell differentiation
GO:0030324 IMP lung development
GO:0030425 IEA dendrite
GO:0030501 IEA positive regulation of bone mineralization
GO:0030509 IGI BMP signaling pathway
GO:0035137 IMP hindlimb morphogenesis
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042733 IGI embryonic digit morphogenesis
GO:0042803 IEA protein homodimerization activity
GO:0043025 IEA neuronal cell body
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046332 IEA SMAD binding
GO:0046872 IEA metal ion binding
GO:0048339 IGI paraxial mesoderm development
GO:0048352 IMP paraxial mesoderm structural organization
GO:0048368 IMP lateral mesoderm development
GO:0048378 IGI regulation of lateral mesodermal cell fate specification
GO:0048382 IMP mesendoderm development
GO:0048568 IMP embryonic organ development
GO:0048589 IMP developmental growth
GO:0048598 IMP embryonic morphogenesis
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0050768 IMP negative regulation of neurogenesis
GO:0051216 IMP cartilage development
GO:0060021 IMP palate development
GO:0060391 IEA positive regulation of SMAD protein import into nucleus
GO:0060896 IMP neural plate pattern specification
GO:0060914 IMP heart formation
GO:2000772 IGI regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000372037 BMPR1A-001 protein_coding Homo_sapiens 0 2662
ENST00000403332 BMPR1APS1-001 processed_pseudogene Homo_sapiens 0 2071
ENST00000527904 BMPR1APS2-001 processed_pseudogene Homo_sapiens 0 1325

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