C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mechanistic target of rapamycin (serine/threonine kinase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000057580 Mtor-002 ENSMUSG00000028991 10090 + 4:148448625-148454973 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JY CIL_0008JY_0002 VISTA 4:148408124-149009196
CIL_0008JG CIL_0008JG_0002 VISTA 4:148444314-149044861
CIL_00019S CIL_00019S_0003 CGP 4:148448611-148557683

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005741 IEA mitochondrial outer membrane
GO:0005764 ISS lysosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0006468 ISO protein phosphorylation
GO:0007281 IDA germ cell development
GO:0008144 IEA drug binding
GO:0010507 IMP negative regulation of autophagy
GO:0010592 IDA positive regulation of lamellipodium assembly
GO:0010831 IGI positive regulation of myotube differentiation
GO:0016242 IMP negative regulation of macroautophagy
GO:0016301 ISO kinase activity
GO:0016605 IDA PML body
GO:0018105 IMP peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0030030 IMP cell projection organization
GO:0030425 IDA dendrite
GO:0030838 IDA positive regulation of actin filament polymerization
GO:0031529 IDA ruffle organization
GO:0031641 IMP regulation of myelination
GO:0031669 IDA cellular response to nutrient levels
GO:0031931 ISO TORC1 complex
GO:0031932 ISO TORC2 complex
GO:0032314 IMP regulation of Rac GTPase activity
GO:0032868 IDA response to insulin
GO:0043022 IDA ribosome binding
GO:0043200 IDA response to amino acid
GO:0045792 IGI negative regulation of cell size
GO:0045859 IGI regulation of protein kinase activity
GO:0046777 ISO protein autophosphorylation
GO:0046889 ISS positive regulation of lipid biosynthetic process
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0051496 IDA positive regulation of stress fiber assembly
GO:0051534 IMP negative regulation of NFAT protein import into nucleus
GO:0071456 IDA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000361445 MTOR-001 protein_coding Homo_sapiens 0 1062

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