C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: purinergic receptor P2X, ligand-gated ion channel, 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000058016 P2rx2-201 ENSMUSG00000029503 10090 - 5:110339812-110343035 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000058016
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000058016 0.512±0.36 0.215±0.13 0.599±0.35 2.011±0.54 0.348±0.17 3.436±1.02 0.052±0.01 0.218±0.11 0.047±0.03 0.473±0.25 0.058±0.00 0.686±0.33 0.433±0.15 30.386±14.83

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000329 CIL_000329_0002 CGP 5:110286306-110343035

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001614 IBA purinergic nucleotide receptor activity
GO:0001666 IMP response to hypoxia
GO:0003029 IMP detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
GO:0003713 ISS transcription coactivator activity
GO:0004931 IDA extracellular ATP-gated cation channel activity
GO:0005507 IEA copper ion binding
GO:0005515 IEA protein binding
GO:0005622 IDA intracellular
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005886 IDA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006812 IDA cation transport
GO:0007268 IMP synaptic transmission
GO:0007274 IMP neuromuscular synaptic transmission
GO:0007528 IMP neuromuscular junction development
GO:0007605 IMP sensory perception of sound
GO:0008144 IEA drug binding
GO:0008270 IEA zinc ion binding
GO:0009743 IMP response to carbohydrate
GO:0009986 IEA cell surface
GO:0010033 IMP response to organic substance
GO:0014069 IEA postsynaptic density
GO:0014832 IGI urinary bladder smooth muscle contraction
GO:0015276 IEA ligand-gated ion channel activity
GO:0016021 IEA integral component of membrane
GO:0016151 IEA nickel cation binding
GO:0016324 ISS apical plasma membrane
GO:0019228 IEA neuronal action potential
GO:0030432 IMP peristalsis
GO:0033198 IMP response to ATP
GO:0035091 IEA phosphatidylinositol binding
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0042734 IEA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0043235 ISO receptor complex
GO:0045340 IEA mercury ion binding
GO:0046870 IEA cadmium ion binding
GO:0048266 IGI behavioral response to pain
GO:0048741 IMP skeletal muscle fiber development
GO:0050897 IEA cobalt ion binding
GO:0050909 IGI sensory perception of taste
GO:0051260 IEA protein homooligomerization
GO:0051291 IEA protein heterooligomerization
GO:0098655 IDA cation transmembrane transport
GO:2001141 ISS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000343948 P2RX2-003 protein_coding Homo_sapiens 0 1038
ENST00000348800 P2RX2-010 protein_coding Homo_sapiens 0 1136
ENST00000350048 P2RX2-009 protein_coding Homo_sapiens 0 832
ENST00000351222 P2RX2-008 protein_coding Homo_sapiens 0 826
ENST00000352418 P2RX2-007 protein_coding Homo_sapiens 0 795
ENST00000389110 P2RX2-006 protein_coding Homo_sapiens 0 1249
ENST00000449132 P2RX2-001 protein_coding Homo_sapiens 0 636
ENST00000542301 P2RX2-002 protein_coding Homo_sapiens 0 966

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