C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine (or cysteine) peptidase inhibitor, clade B, member 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086690 Serpinb7-001 ENSMUSG00000067001 10090 + 1:107422689-107452689 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000086690
Transcript ID Adipose Bladder Brain Breast Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000086690 0.112±0.00 0.004±0.00 0.063±0.01 0.409±0.22 0.035±0.01 0.026±0.02 0.059±0.05 0.013±0.00 0.010±0.01 0.046±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_000E CGP 1:107361198-107452689
CIL_000160 CIL_000160_000S CGP 1:107399655-107535478

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005575 ND cellular_component
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0032914 IEA positive regulation of transforming growth factor beta1 production
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0072126 IEA positive regulation of glomerular mesangial cell proliferation
GO:0090362 IEA positive regulation of platelet-derived growth factor production

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336429 SERPINB7-201 protein_coding Homo_sapiens 0 931
ENST00000398019 SERPINB7-001 protein_coding Homo_sapiens 0 931
ENST00000425392 SERPINB7-002 protein_coding Homo_sapiens 0 311
ENST00000431370 SERPINB7-005 protein_coding Homo_sapiens 0 311
ENST00000447428 SERPINB7-004 protein_coding Homo_sapiens 0 429
ENST00000540675 SERPINB7-202 protein_coding Homo_sapiens 0 778
ENST00000546027 SERPINB7-203 protein_coding Homo_sapiens 0 977

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