C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000097563 Cd74-202 ENSMUSG00000024610 10090 + 18:60803848-60812646 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097563
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097563 97.169±5.44 80.261±12.37 56.047±7.76 0.240±0.15 315.457±65.22 104.577±13.09 17.668±7.55 41.713±1.55 10.922±9.19 228.746±55.42 5.566±4.58 86.413±26.56 3.204±4.73 1.456±0.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091Q CIL_00091Q_0002 VISTA 18:60604549-61207221

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001516 ISS prostaglandin biosynthetic process
GO:0001540 IEA beta-amyloid binding
GO:0001961 IMP positive regulation of cytokine-mediated signaling pathway
GO:0002606 IDA positive regulation of dendritic cell antigen processing and presentation
GO:0002792 IEA negative regulation of peptide secretion
GO:0002821 NAS positive regulation of adaptive immune response
GO:0002830 IMP positive regulation of type 2 immune response
GO:0002906 IMP negative regulation of mature B cell apoptotic process
GO:0004896 IMP cytokine receptor activity
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005771 IDA multivesicular body
GO:0005773 IEA vacuole
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006461 IDA protein complex assembly
GO:0006886 IDA intracellular protein transport
GO:0006952 IMP defense response
GO:0007165 IEA signal transduction
GO:0008283 ISS cell proliferation
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016064 IMP immunoglobulin mediated immune response
GO:0019882 IDA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019955 ISS cytokine binding
GO:0023026 IEA MHC class II protein complex binding
GO:0030890 IEA positive regulation of B cell proliferation
GO:0035691 IDA macrophage migration inhibitory factor signaling pathway
GO:0035692 IDA macrophage migration inhibitory factor receptor complex
GO:0035693 IDA NOS2-CD74 complex
GO:0035718 IEA macrophage migration inhibitory factor binding
GO:0042289 IPI MHC class II protein binding
GO:0042613 IDA MHC class II protein complex
GO:0042658 IEA MHC class II protein binding, via antigen binding groove
GO:0043066 ISS negative regulation of apoptotic process
GO:0043518 IMP negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044183 IEA protein binding involved in protein folding
GO:0045059 IMP positive thymic T cell selection
GO:0045060 IMP negative thymic T cell selection
GO:0045089 IC positive regulation of innate immune response
GO:0045581 IMP negative regulation of T cell differentiation
GO:0045582 IMP positive regulation of T cell differentiation
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0050998 IPI nitric-oxide synthase binding
GO:0051085 IMP chaperone mediated protein folding requiring cofactor
GO:0060907 IDA positive regulation of macrophage cytokine production
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0090023 IDA positive regulation of neutrophil chemotaxis
GO:1902166 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000343 IDA positive regulation of chemokine (C-X-C motif) ligand 2 production

Homologs

No Homologs available.

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