Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	additional sex combs like 2 (Drosophila)
ENSMUST00000153102	Asxl2-006	ENSMUSG00000037486	10090	+	12:3426901-3502466	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Breast	Colon	Heart	Kidney	Liver	Lung	Ovary	Placenta	Testis
ENSMUST00000153102	2.335±0.53	5.670±0.35	4.528±1.37	2.807±0.64	1.063±0.10	2.418±0.12	1.694±0.33	2.484±0.86	7.281±1.85	4.527±1.11	4.209±0.50

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000122	IMP	negative regulation of transcription from RNA polymerase II promoter
GO:0000790	IDA	nuclear chromatin
GO:0003677	IEA	DNA binding
GO:0005634	IDA	nucleus
GO:0006351	IEA	transcription, DNA-templated
GO:0007507	IMP	heart development
GO:0007512	IMP	adult heart development
GO:0035360	IEA	positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0042975	IEA	peroxisome proliferator activated receptor binding
GO:0045600	IEA	positive regulation of fat cell differentiation
GO:0045672	IMP	positive regulation of osteoclast differentiation
GO:0045944	IEA	positive regulation of transcription from RNA polymerase II promoter
GO:0048704	IMP	embryonic skeletal system morphogenesis
GO:1900159	IMP	positive regulation of bone mineralization involved in bone maturation
GO:1902466	IMP	positive regulation of histone H3-K27 trimethylation

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENST00000336112	ASXL2-201	protein_coding	Homo_sapiens	0	3271
ENST00000404843	ASXL2-004	protein_coding	Homo_sapiens	0	1600
ENST00000435504	ASXL2-001	protein_coding	Homo_sapiens	0	3271
ENST00000497092	ASXL2-003	processed_transcript	Homo_sapiens	0	558

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