C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tissue inhibitor of metalloproteinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000155707 Timp2-002 ENSMUSG00000017466 10090 - 11:118303701-118355740 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryPlacentaTestisENSMUST00000155707
Transcript ID Brain Ovary Placenta Testis
ENSMUST00000155707 60.407±0.00 108.022±19.85 27.081±25.03 62.721±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003UE CIL_0003UE_0003 CGP 11:118259651-118355740
CIL_00062J CIL_00062J_0002 CGP 11:118301069-118355740

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005178 IDA integrin binding
GO:0005604 IDA basement membrane
GO:0008047 IMP enzyme activator activity
GO:0008191 TAS metalloendopeptidase inhibitor activity
GO:0008285 IDA negative regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030814 IDA regulation of cAMP metabolic process
GO:0043408 IDA regulation of MAPK cascade
GO:0045664 IDA regulation of neuron differentiation
GO:0071310 IDA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262768 TIMP2-001 protein_coding Homo_sapiens 0 726
ENST00000536189 TIMP2-003 protein_coding Homo_sapiens 0 728
ENST00000585421 TIMP2-008 protein_coding Homo_sapiens 0 723
ENST00000586057 TIMP2-004 protein_coding Homo_sapiens 0 728
ENST00000586713 KIAA1731NL-004 protein_coding Homo_sapiens 0 257
ENST00000592761 TIMP2-002 nonsense_mediated_decay Homo_sapiens 0 448

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