C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: toll-like receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000167106 Tlr3-202 ENSMUSG00000031639 10090 - 8:45395911-45410608 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000167106
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000167106 0.756±0.34 1.831±0.82 1.312±0.32 0.068±0.01 1.947±0.89 2.071±0.71 0.911±0.34 1.178±0.22 0.374±0.18 3.256±1.19 0.217±0.10 1.002±0.54 0.487±0.28 0.211±0.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002756 IEA MyD88-independent toll-like receptor signaling pathway
GO:0003725 ISS double-stranded RNA binding
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0006952 IMP defense response
GO:0006954 IEA inflammatory response
GO:0009615 IMP response to virus
GO:0016021 IEA integral component of membrane
GO:0032481 IDA positive regulation of type I interferon production
GO:0032728 IDA positive regulation of interferon-beta production
GO:0032735 IDA positive regulation of interleukin-12 production
GO:0032755 IDA positive regulation of interleukin-6 production
GO:0032760 IDA positive regulation of tumor necrosis factor production
GO:0034138 IEA toll-like receptor 3 signaling pathway
GO:0034346 IDA positive regulation of type III interferon production
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 IMP response to exogenous dsRNA
GO:0045078 ISS positive regulation of interferon-gamma biosynthetic process
GO:0045080 IMP positive regulation of chemokine biosynthetic process
GO:0045087 TAS innate immune response
GO:0045356 ISS positive regulation of interferon-alpha biosynthetic process
GO:0045359 ISS positive regulation of interferon-beta biosynthetic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IDA positive regulation of JNK cascade
GO:0050729 IEA positive regulation of inflammatory response
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051607 TAS defense response to virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000296795 TLR3-001 protein_coding Homo_sapiens 0 2274
ENST00000504367 TLR3-003 protein_coding Homo_sapiens 0 1844
ENST00000512264 TLR3-004 retained_intron Homo_sapiens 0 1840

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