C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: heme oxygenase (decycling) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000216117 HMOX1-001 ENSG00000100292 9606 + 22:35380835-35394214 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216117
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216117 29.109±0.00 47.878±0.00 2.377±0.00 3.446±2.86 10.029±9.61 4.042±1.98 2.011±1.52 27.726±23.56 52.075±50.90 30.348±28.68 15.846±0.00 44.871±44.57 61.857±21.78 8.368±2.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099W CIL_00099W_0001 VISTA 22:35286634-35891311
CIL_0002NF CIL_0002NF_0001 CGP 22:35299275-35394214
CIL_00094Q CIL_00094Q_0001 VISTA 22:35329925-35944605
CIL_0006NI CIL_0006NI_0002 CGP 22:35380361-35425430

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 TAS angiogenesis
GO:0001666 IEA response to hypoxia
GO:0001935 TAS endothelial cell proliferation
GO:0002246 IMP wound healing involved in inflammatory response
GO:0002686 TAS negative regulation of leukocyte migration
GO:0004392 IDA:IEA heme oxygenase (decyclizing) activity
GO:0004630 IEA phospholipase D activity
GO:0004871 IMP signal transducer activity
GO:0005515 IEA protein binding
GO:0005615 TAS extracellular space
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005783 ISS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005829 IEA cytosol
GO:0005901 IEA caveola
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006788 IEA:IDA heme oxidation
GO:0006879 TAS cellular iron ion homeostasis
GO:0006979 IMP response to oxidative stress
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007588 IC excretion
GO:0008217 IEA regulation of blood pressure
GO:0008219 ISS cell death
GO:0008285 IEA negative regulation of cell proliferation
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010656 IEA negative regulation of muscle cell apoptotic process
GO:0014806 TAS smooth muscle hyperplasia
GO:0016020 TAS membrane
GO:0016491 IEA oxidoreductase activity
GO:0019899 ISS enzyme binding
GO:0020037 IDA heme binding
GO:0031670 IEA cellular response to nutrient
GO:0032764 IEA negative regulation of mast cell cytokine production
GO:0034101 IMP erythrocyte homeostasis
GO:0034383 TAS low-density lipoprotein particle clearance
GO:0034395 IEA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0035094 IDA response to nicotine
GO:0035556 TAS intracellular signal transduction
GO:0042167 IDA heme catabolic process
GO:0042168 IEA heme metabolic process
GO:0042542 ISS response to hydrogen peroxide
GO:0042803 IDA protein homodimerization activity
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043305 IEA negative regulation of mast cell degranulation
GO:0043392 IEA negative regulation of DNA binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043619 ISS regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043627 IEA response to estrogen
GO:0044281 TAS small molecule metabolic process
GO:0045080 TAS positive regulation of chemokine biosynthetic process
GO:0045765 TAS regulation of angiogenesis
GO:0045766 IEA positive regulation of angiogenesis
GO:0045909 IC positive regulation of vasodilation
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048661 IDA positive regulation of smooth muscle cell proliferation
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0051090 ISS regulation of sequence-specific DNA binding transcription factor activity
GO:0051260 IDA protein homooligomerization
GO:0055072 IDA iron ion homeostasis
GO:0055085 TAS transmembrane transport
GO:0055114 IEA oxidation-reduction process
GO:0071243 IEA cellular response to arsenic-containing substance
GO:0071276 IEA cellular response to cadmium ion
GO:0071456 IEP cellular response to hypoxia
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

No Homologs available.

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