C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: purinergic receptor P2X, ligand-gated ion channel, 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000225538 P2RX1-002 ENSG00000108405 9606 - 17:3896592-3916500 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225538
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225538 1.256±0.00 5.232±0.00 0.321±0.00 0.402±0.09 1.015±0.00 0.111±0.04 0.695±0.00 2.623±2.51 0.910±0.59 0.150±0.13 0.722±0.48 4.387±2.88 2.943±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060Y CIL_00060Y_0002 CGP 17:3860315-3916500

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001614 IDA:IEA purinergic nucleotide receptor activity
GO:0002554 IEA serotonin secretion by platelet
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0004931 IBA extracellular ATP-gated cation channel activity
GO:0005216 IEA ion channel activity
GO:0005261 IDA cation channel activity
GO:0005262 TAS calcium channel activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006811 IDA:IEA ion transport
GO:0006812 IBA cation transport
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006940 IEA regulation of smooth muscle contraction
GO:0007165 TAS signal transduction
GO:0007320 IEA insemination
GO:0007596 TAS blood coagulation
GO:0008144 IEA drug binding
GO:0008217 IEA regulation of blood pressure
GO:0008270 IEA zinc ion binding
GO:0010033 IEA response to organic substance
GO:0016020 IEA membrane
GO:0019228 IEA neuronal action potential
GO:0019229 IEA regulation of vasoconstriction
GO:0030168 IEA platelet activation
GO:0031240 IEA external side of cell outer membrane
GO:0033198 IEA response to ATP
GO:0035249 IEA synaptic transmission, glutamatergic
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0042310 IEA vasoconstriction
GO:0043005 IEA neuron projection
GO:0043234 IEA protein complex
GO:0043270 IEA positive regulation of ion transport
GO:0045121 IEA membrane raft
GO:0045211 IEA postsynaptic membrane
GO:0046513 IEA ceramide biosynthetic process
GO:0051260 IEA protein homooligomerization
GO:0051291 IEA protein heterooligomerization
GO:0051924 IEA regulation of calcium ion transport
GO:0070588 TAS calcium ion transmembrane transport
GO:0098655 IBA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021141 P2rx1-001 protein_coding Mus_musculus 0 1393
ENSMUST00000148964 P2rx1-003 retained_intron Mus_musculus 0 719
ENSMUST00000092938 P2rx1-002 protein_coding Mus_musculus 0 715

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