C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: heparin-binding EGF-like growth factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000230990 HBEGF-001 ENSG00000113070 9606 - 5:140332843-140346631 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000230990
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000230990 39.678±0.00 3.026±0.00 0.929±0.00 5.564±3.90 3.429±1.42 8.091±7.90 4.441±3.02 2.832±0.00 0.849±0.40 41.229±38.12 8.726±5.55 5.274±3.39 5.348±1.33 4.892±1.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00062T CIL_00062T_0002 CGP 5:140245039-140346631
CIL_0006ZL CIL_0006ZL_0001 CGP 5:140332843-140375143

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 ISS extracellular space
GO:0005887 ISS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0007173 IMP epidermal growth factor receptor signaling pathway
GO:0007517 TAS muscle organ development
GO:0008016 IEA regulation of heart contraction
GO:0008083 IDA growth factor activity
GO:0008201 IMP heparin binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009986 IDA cell surface
GO:0016477 IEA cell migration
GO:0030307 IEA positive regulation of cell growth
GO:0030335 IMP positive regulation of cell migration
GO:0035313 IEA wound healing, spreading of epidermal cells
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051545 IEA negative regulation of elastin biosynthetic process
GO:0051549 IEA positive regulation of keratinocyte migration
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0090303 IMP positive regulation of wound healing

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025363 Hbegf-201 protein_coding Mus_musculus 0 1273

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