C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: epithelial cell transforming 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000232458 ECT2-001 ENSG00000114346 9606 + 3:172750682-172821474 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000232458
Transcript ID Adrenal Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000232458 0.192±0.00 0.906±0.00 1.004±0.53 1.058±0.57 0.760±0.00 0.763±0.00 0.651±0.00 3.810±4.22 0.935±0.00 2.628±0.13

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0000910 IEA:IMP cytokinesis
GO:0004871 IMP signal transducer activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IDA:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA:IMP GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IEA:IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005911 IDA cell-cell junction
GO:0005923 IDA tight junction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0030496 IDA midbody
GO:0032147 IDA activation of protein kinase activity
GO:0032154 IDA cleavage furrow
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032467 IMP positive regulation of cytokinesis
GO:0032862 IDA activation of Rho GTPase activity
GO:0032863 IMP activation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0042307 ISS positive regulation of protein import into nucleus
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043089 IDA positive regulation of Cdc42 GTPase activity
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043547 IEA positive regulation of GTPase activity
GO:0045666 IEA:ISS positive regulation of neuron differentiation
GO:0045859 IDA regulation of protein kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0051260 IDA protein homooligomerization
GO:0051988 IMP regulation of attachment of spindle microtubules to kinetochore
GO:0070301 IDA cellular response to hydrogen peroxide
GO:0070830 IMP tight junction assembly
GO:0071277 IDA cellular response to calcium ion
GO:0071479 IDA cellular response to ionizing radiation
GO:0072686 IDA mitotic spindle
GO:0097149 IDA centralspindlin complex
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000176242 Ect2-201 protein_coding Mus_musculus 0 2963
ENSMUST00000108298 Ect2-001 protein_coding Mus_musculus 0 2963
ENSMUST00000108300 Ect2-002 protein_coding Mus_musculus 0 2787
ENSMUST00000184113 Ect2-003 nonsense_mediated_decay Mus_musculus 0 2645
ENSMUST00000108296 Ect2-004 retained_intron Mus_musculus 0 2233
ENSMUST00000150061 Ect2-006 nonsense_mediated_decay Mus_musculus 0 562
ENSMUST00000176908 Ect2-011 retained_intron Mus_musculus 1e-27 130

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