C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Cbl proto-oncogene C, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000270279 CBLC-001 ENSG00000142273 9606 + 19:44777869-44800634 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000270279
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000270279 0.165±0.00 0.397±0.00 0.051±0.00 1.110±0.69 3.904±1.85 2.244±1.81 2.385±2.28 0.594±0.37 6.104±8.05 0.690±0.50 0.575±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044F CIL_00044F_0002 CGP 19:44747705-44800634

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001784 IDA phosphotyrosine binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0004871 IEA signal transducer activity
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007175 IDA negative regulation of epidermal growth factor-activated receptor activity
GO:0008270 IEA zinc ion binding
GO:0016874 IEA ligase activity
GO:0017124 IDA SH3 domain binding
GO:0042059 IDA negative regulation of epidermal growth factor receptor signaling pathway
GO:0042787 IDA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043822 Cblc-001 protein_coding Mus_musculus 0 1066
ENSMUST00000145755 Cblc-005 processed_transcript Mus_musculus 0 488
ENSMUST00000125050 Cblc-007 processed_transcript Mus_musculus 0 292

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