C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000309877 IRF3-006 ENSG00000126456 9606 - 19:49659572-49665169 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000309877
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000309877 7.279±0.00 21.929±0.00 2.857±2.40 7.998±0.00 4.116±3.29 3.087±0.00 6.088±5.59 2.698±0.00 12.915±12.20 1.287±0.00 17.384±5.90 12.896±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 NAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003712 TAS transcription cofactor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006915 TAS apoptotic process
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032480 TAS negative regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0032727 ISS positive regulation of interferon-alpha production
GO:0032728 ISS positive regulation of interferon-beta production
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0039530 TAS MDA-5 signaling pathway
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0045087 TAS innate immune response
GO:0051607 ISS defense response to virus
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071888 TAS macrophage apoptotic process

Homologs

No Homologs available.

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