C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: alpha-2-macroglobulin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000318602 A2M-001 ENSG00000175899 9606 - 12:9067712-9116157 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318602
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318602 235.505±0.00 179.000±0.00 12.179±0.00 22.370±3.18 99.652±18.58 106.278±93.08 65.289±49.58 90.384±28.72 54.565±0.00 477.397±359.12 21.517±14.39 50.474±22.21 121.151±56.18 49.861±41.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HL CIL_0008HL_0001 VISTA 12:8543390-9149656
CIL_0000TB CIL_0000TB_0009 CGP 12:9067664-9208370

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001869 IDA negative regulation of complement activation, lectin pathway
GO:0002020 IPI protease binding
GO:0002576 TAS platelet degranulation
GO:0004866 IEA endopeptidase inhibitor activity
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005102 IMP receptor binding
GO:0005515 IPI protein binding
GO:0005576 NAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005829 TAS cytosol
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0007597 TAS blood coagulation, intrinsic pathway
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0019838 IDA growth factor binding
GO:0019899 IPI enzyme binding
GO:0019959 IPI interleukin-8 binding
GO:0019966 IDA interleukin-1 binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0031093 TAS platelet alpha granule lumen
GO:0043120 IDA tumor necrosis factor binding
GO:0048306 IPI calcium-dependent protein binding
GO:0048863 IEA stem cell differentiation
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000032203 A2m-201 protein_coding Mus_musculus 0 1912
ENSMUST00000112132 Pzp-201 protein_coding Mus_musculus 0 616
ENSMUST00000032510 Pzp-001 protein_coding Mus_musculus 0 616

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