C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adiponectin, C1Q and collagen domain containing
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000320741 ADIPOQ-002 ENSG00000181092 9606 + 3:186842690-186858463 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320741
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320741 82.184±0.00 0.416±0.00 0.076±0.00 134.063±127.79 2.734±1.75 1.783±0.50 0.046±0.03 6.304±6.27 0.659±0.48 0.771±0.45 0.108±0.13 0.013±0.01 0.302±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LA CIL_0008LA_0001 VISTA 3:186647123-187250687
CIL_000048 CIL_000048_0001 CGP 3:186789880-186858463

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0005102 ISS receptor binding
GO:0005125 NAS cytokine activity
GO:0005179 IDA hormone activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005581 IEA collagen trimer
GO:0005615 IDA extracellular space
GO:0005783 ISS endoplasmic reticulum
GO:0006006 ISS glucose metabolic process
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006635 ISS fatty acid beta-oxidation
GO:0009749 ISS response to glucose
GO:0009967 ISS positive regulation of signal transduction
GO:0009986 IDA cell surface
GO:0010642 IDA negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0010739 IDA positive regulation of protein kinase A signaling
GO:0010745 IDA negative regulation of macrophage derived foam cell differentiation
GO:0010804 IDA negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0010906 IDA regulation of glucose metabolic process
GO:0014912 IDA negative regulation of smooth muscle cell migration
GO:0019395 ISS fatty acid oxidation
GO:0030336 ISS negative regulation of cell migration
GO:0030853 IDA negative regulation of granulocyte differentiation
GO:0031953 IDA negative regulation of protein autophosphorylation
GO:0032270 IDA positive regulation of cellular protein metabolic process
GO:0032720 IDA negative regulation of tumor necrosis factor production
GO:0032757 IDA positive regulation of interleukin-8 production
GO:0032869 ISS cellular response to insulin stimulus
GO:0033034 IDA positive regulation of myeloid cell apoptotic process
GO:0033691 IDA sialic acid binding
GO:0034115 IDA negative regulation of heterotypic cell-cell adhesion
GO:0034383 IDA low-density lipoprotein particle clearance
GO:0034612 IDA response to tumor necrosis factor
GO:0035690 ISS cellular response to drug
GO:0042593 ISS glucose homeostasis
GO:0042802 TAS identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045650 IDA negative regulation of macrophage differentiation
GO:0045715 IDA negative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0045721 ISS negative regulation of gluconeogenesis
GO:0045776 IDA negative regulation of blood pressure
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045923 ISS positive regulation of fatty acid metabolic process
GO:0046326 ISS positive regulation of glucose import
GO:0048662 IDA negative regulation of smooth muscle cell proliferation
GO:0050728 ISS negative regulation of inflammatory response
GO:0050765 IDA negative regulation of phagocytosis
GO:0050805 IDA negative regulation of synaptic transmission
GO:0050873 ISS brown fat cell differentiation
GO:0051260 ISS protein homooligomerization
GO:0070062 IDA extracellular vesicular exosome
GO:0070373 IDA negative regulation of ERK1 and ERK2 cascade
GO:0070994 ISS detection of oxidative stress
GO:0071639 IDA positive regulation of monocyte chemotactic protein-1 production
GO:0072659 IDA protein localization to plasma membrane
GO:0090317 IDA negative regulation of intracellular protein transport
GO:1900121 IDA negative regulation of receptor binding
GO:2000279 IDA negative regulation of DNA biosynthetic process
GO:2000467 ISS positive regulation of glycogen (starch) synthase activity
GO:2000478 ISS positive regulation of metanephric glomerular visceral epithelial cell development
GO:2000481 IDA positive regulation of cAMP-dependent protein kinase activity
GO:2000534 IDA positive regulation of renal albumin absorption
GO:2000584 ISS negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:2000590 ISS negative regulation of metanephric mesenchymal cell migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023593 Adipoq-001 protein_coding Mus_musculus 0 610

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