C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CASP8 and FADD-like apoptosis regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000342795 CFLAR-007 ENSG00000003402 9606 + 2:201116239-201154576 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006508 IEA proteolysis
GO:0006915 IMP apoptotic process
GO:0007519 ISS skeletal muscle tissue development
GO:0008047 IDA enzyme activator activity
GO:0014732 ISS skeletal muscle atrophy
GO:0014842 ISS regulation of satellite cell proliferation
GO:0014866 ISS skeletal myofibril assembly
GO:0016032 IEA viral process
GO:0031264 IDA death-inducing signaling complex
GO:0035877 IBA death effector domain binding
GO:0042981 IEA regulation of apoptotic process
GO:0043085 IDA positive regulation of catalytic activity
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043403 ISS skeletal muscle tissue regeneration
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0060544 IDA regulation of necroptotic process
GO:0097190 TAS apoptotic signaling pathway
GO:0097342 IDA ripoptosome
GO:1901740 ISS negative regulation of myoblast fusion
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway
GO:2001239 TAS regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105140 AW011738-201 protein_coding Mus_musculus 0.0001 53

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