C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adaptor-related protein complex 2, alpha 1 subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354293 AP2A1-001 ENSG00000196961 9606 + 19:49766968-49807112 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354293
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354293 35.242±0.00 16.614±0.00 1.011±0.00 2.500±0.00 6.905±0.00 0.755±0.00 3.280±0.00 12.350±0.00 0.954±0.00 44.505±0.00 43.222±29.13 59.132±10.10 87.692±39.50

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006886 NAS:IEA intracellular protein transport
GO:0006895 NAS Golgi to endosome transport
GO:0006897 NAS endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008565 IEA protein transporter activity
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 ISS protein kinase binding
GO:0030117 IEA membrane coat
GO:0030122 NAS AP-2 adaptor complex
GO:0030130 NAS clathrin coat of trans-Golgi network vesicle
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus
GO:1900126 IMP negative regulation of hyaluronan biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167930 Ap2a1-202 protein_coding Mus_musculus 0 4024
ENSMUST00000107857 Ap2a1-002 protein_coding Mus_musculus 0 3991
ENSMUST00000085399 Ap2a1-201 protein_coding Mus_musculus 0 2811
ENSMUST00000166972 Ap2a1-001 protein_coding Mus_musculus 0 2811
ENSMUST00000003038 Ap2a2-201 protein_coding Mus_musculus 0 1592
ENSDART00000076469 ap2a1-201 protein_coding Danio_rerio 0 1434
ENSDART00000155967 ap2a1-001 protein_coding Danio_rerio 0 1434
ENSMUST00000164575 Ap2a1-004 nonsense_mediated_decay Mus_musculus 0 865
ENSMUST00000165890 Ap2a1-008 protein_coding Mus_musculus 0 701
ENSMUST00000166060 Ap2a1-007 retained_intron Mus_musculus 0 662
ENSMUST00000170656 Ap2a1-009 retained_intron Mus_musculus 0 422
ENSMUST00000169527 Ap2a1-005 processed_transcript Mus_musculus 0 270
ENSMUST00000171169 Fuz-005 retained_intron Mus_musculus 0 228
ENSMUST00000164374 Fuz-007 retained_intron Mus_musculus 0 228
ENSMUST00000071207 Fuz-001 protein_coding Mus_musculus 0 226
ENSMUST00000168389 Fuz-002 protein_coding Mus_musculus 0 219
ENSMUST00000168207 Fuz-011 protein_coding Mus_musculus 0.000001 60

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