C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: axin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354866 AXIN1-002 ENSG00000103126 9606 - 16:287441-352449 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000354866
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000354866 4.424±0.00 5.895±0.00 1.441±0.57 2.066±0.27 3.758±3.25 1.164±0.74 0.886±0.00 0.853±0.19 2.159±1.37 5.827±2.05 3.968±0.92 1.040±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00094P CIL_00094P_0001 VISTA 16:-195470-405616
CIL_0008HK CIL_0008HK_0001 VISTA 16:-187027-414801

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001743 IBA optic placode formation
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0004871 IDA signal transducer activity
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005881 IBA cytoplasmic microtubule
GO:0005938 IBA cell cortex
GO:0006915 IEA apoptotic process
GO:0007257 IBA activation of JUN kinase activity
GO:0007368 IBA determination of left/right symmetry
GO:0008013 IDA beta-catenin binding
GO:0008219 IBA cell death
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0009950 IBA dorsal/ventral axis specification
GO:0010800 NAS positive regulation of peptidyl-threonine phosphorylation
GO:0014069 IBA postsynaptic density
GO:0016023 IBA cytoplasmic membrane-bounded vesicle
GO:0016328 IDA lateral plasma membrane
GO:0019899 IPI enzyme binding
GO:0019901 ISS protein kinase binding
GO:0021797 IBA forebrain anterior/posterior pattern specification
GO:0021881 IBA Wnt-activated signaling pathway involved in forebrain neuron fate commitment
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030877 IDA beta-catenin destruction complex
GO:0030910 IBA olfactory placode formation
GO:0031122 IBA cytoplasmic microtubule organization
GO:0031398 NAS positive regulation of protein ubiquitination
GO:0031410 ISS cytoplasmic vesicle
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032147 IDA activation of protein kinase activity
GO:0032947 IMP protein complex scaffold
GO:0033138 NAS positive regulation of peptidyl-serine phosphorylation
GO:0035412 IBA regulation of catenin import into nucleus
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0042802 ISS identical protein binding
GO:0042803 ISS protein homodimerization activity
GO:0043547 IBA positive regulation of GTPase activity
GO:0043623 IDA cellular protein complex assembly
GO:0045599 IBA negative regulation of fat cell differentiation
GO:0045732 IC positive regulation of protein catabolic process
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046330 ISS positive regulation of JNK cascade
GO:0046332 IPI SMAD binding
GO:0048048 IBA embryonic eye morphogenesis
GO:0048320 IBA axial mesoderm formation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051443 IMP positive regulation of ubiquitin-protein transferase activity
GO:0055001 IBA muscle cell development
GO:0060070 IC canonical Wnt signaling pathway
GO:0060272 IBA embryonic skeletal joint morphogenesis
GO:0060823 IBA canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0070016 ISS armadillo repeat domain binding
GO:0070411 IPI I-SMAD binding
GO:0071407 IBA cellular response to organic cyclic compound
GO:0071944 IDA cell periphery
GO:0090090 IBA negative regulation of canonical Wnt signaling pathway
GO:0090244 IBA Wnt signaling pathway involved in somitogenesis
GO:2000060 ISS positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000163421 Axin1-002 protein_coding Mus_musculus 0 2362
ENSMUST00000118904 Axin1-201 protein_coding Mus_musculus 0 2357
ENSMUST00000074370 Axin1-001 protein_coding Mus_musculus 0 2008
ENSDART00000033369 axin1-001 protein_coding Danio_rerio 0 472
ENSMUST00000168282 Axin1-004 protein_coding Mus_musculus 0 241

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