C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dual serine/threonine and tyrosine protein kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367161 DSTYK-002 ENSG00000133059 9606 - 1:205142505-205211566 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367161
Transcript ID Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367161 0.530±0.00 1.245±0.00 0.415±0.00 1.073±0.22 0.640±0.00 0.615±0.37 0.270±0.00 0.899±0.00 0.805±0.06 1.027±0.39 1.148±0.81 1.143±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0016323 IDA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0033674 IMP positive regulation of kinase activity
GO:0044344 IDA cellular response to fibroblast growth factor stimulus
GO:0045743 IMP positive regulation of fibroblast growth factor receptor signaling pathway
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000188389 Dstyk-004 protein_coding Mus_musculus 0 3369
ENSMUST00000045110 Dstyk-001 protein_coding Mus_musculus 0 2983
ENSMUST00000187092 Dstyk-007 protein_coding Mus_musculus 0 647
ENSMUST00000188006 Dstyk-005 retained_intron Mus_musculus 0 601

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