C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenosine A1 receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367236 ADORA1-001 ENSG00000163485 9606 + 1:203127065-203167405 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001609 IEA G-protein coupled adenosine receptor activity
GO:0001659 IEA temperature homeostasis
GO:0001664 IEA G-protein coupled receptor binding
GO:0001666 IEA response to hypoxia
GO:0001883 IEA purine nucleoside binding
GO:0001973 IEA adenosine receptor signaling pathway
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0002674 IEA negative regulation of acute inflammatory response
GO:0002686 IEA negative regulation of leukocyte migration
GO:0002793 IEA positive regulation of peptide secretion
GO:0003093 IEA regulation of glomerular filtration
GO:0004629 IEA phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006612 IEA protein targeting to membrane
GO:0006909 TAS phagocytosis
GO:0006954 TAS inflammatory response
GO:0007165 TAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007399 TAS nervous system development
GO:0008285 IEA negative regulation of cell proliferation
GO:0012505 IEA endomembrane system
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014069 IEA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0016042 IEA lipid catabolic process
GO:0016323 IEA basolateral plasma membrane
GO:0030425 IEA dendrite
GO:0030673 IEA axolemma
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0032244 IEA positive regulation of nucleoside transport
GO:0032279 IEA asymmetric synapse
GO:0032795 IEA heterotrimeric G-protein binding
GO:0032900 IEA negative regulation of neurotrophin production
GO:0035307 IEA positive regulation of protein dephosphorylation
GO:0035814 IEA negative regulation of renal sodium excretion
GO:0042321 IEA negative regulation of circadian sleep/wake cycle, sleep
GO:0042323 IEA negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0042734 IEA presynaptic membrane
GO:0043025 IEA neuronal cell body
GO:0043066 IEA negative regulation of apoptotic process
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0043268 IEA positive regulation of potassium ion transport
GO:0044297 IEA cell body
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045741 IEA positive regulation of epidermal growth factor-activated receptor activity
GO:0045776 IEA negative regulation of blood pressure
GO:0045777 IEA positive regulation of blood pressure
GO:0045822 IEA negative regulation of heart contraction
GO:0045908 IEA negative regulation of vasodilation
GO:0046888 IEA negative regulation of hormone secretion
GO:0046982 IEA protein heterodimerization activity
GO:0048167 IEA regulation of synaptic plasticity
GO:0048786 IEA presynaptic active zone
GO:0050728 IEA negative regulation of inflammatory response
GO:0050890 IEA cognition
GO:0050965 IEA detection of temperature stimulus involved in sensory perception of pain
GO:0050995 IEA negative regulation of lipid catabolic process
GO:0051930 IEA regulation of sensory perception of pain
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0055118 IEA negative regulation of cardiac muscle contraction
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0060087 IEA relaxation of vascular smooth muscle
GO:0070256 IEA negative regulation of mucus secretion
GO:0097190 TAS apoptotic signaling pathway
GO:1900453 IEA negative regulation of long term synaptic depression

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000086465 Adora1-001 protein_coding Mus_musculus 0 1406
ENSMUST00000169927 Adora1-201 protein_coding Mus_musculus 0 1288
ENSMUST00000038191 Adora1-002 protein_coding Mus_musculus 0 1288
ENSMUST00000187631 Adora1-004 protein_coding Mus_musculus 0 702
ENSDART00000112926 adora1-001 protein_coding Danio_rerio 0 195

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