C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cytochrome b5 reductase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369681 CYB5R4-001 ENSG00000065615 9606 + 6:83859643-83967424 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369681
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369681 1.178±0.00 1.852±0.00 0.192±0.00 1.184±0.00 0.746±0.22 0.666±0.13 0.678±0.41 0.668±0.37 0.650±0.12 0.811±0.02 0.441±0.31 0.572±0.17 0.528±0.05 2.145±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000819 CIL_000819_0001 VISTA 6:83751774-84353626
CIL_000676 CIL_000676_0001 CGP 6:83853266-83967424
CIL_00071Q CIL_00071Q_0001 CGP 6:83859643-84090881

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003032 NAS detection of oxygen
GO:0003958 IEA NADPH-hemoprotein reductase activity
GO:0004128 IDA cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005515 IEA protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0006091 IDA generation of precursor metabolites and energy
GO:0006739 IEA NADP metabolic process
GO:0006801 IDA superoxide metabolic process
GO:0016174 IDA NAD(P)H oxidase activity
GO:0016491 IEA oxidoreductase activity
GO:0016653 IDA oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
GO:0020037 IEA heme binding
GO:0030073 ISS insulin secretion
GO:0042593 ISS glucose homeostasis
GO:0046677 ISS response to antibiotic
GO:0046872 IEA metal ion binding
GO:0048468 ISS cell development
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IDA:IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168529 Cyb5r4-001 protein_coding Mus_musculus 0 1629
ENSMUST00000174724 Cyb5r4-002 processed_transcript Mus_musculus 0 1430
ENSMUST00000121594 Gm11868-001 processed_pseudogene Mus_musculus 0 1336
ENSMUST00000174043 Cyb5r4-005 retained_intron Mus_musculus 0 1070
ENSMUST00000174540 Cyb5r4-004 retained_intron Mus_musculus 0 254

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