C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 24-dehydrocholesterol reductase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000371269 DHCR24-001 ENSG00000116133 9606 - 1:54849633-54887218 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartENST00000371269
Transcript ID Heart
ENST00000371269 0.366±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000246 IMP delta24(24-1) sterol reductase activity
GO:0003824 IEA catalytic activity
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 NAS endoplasmic reticulum membrane
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0006695 ISS cholesterol biosynthetic process
GO:0006915 NAS apoptotic process
GO:0006979 IEP response to oxidative stress
GO:0007050 NAS cell cycle arrest
GO:0007265 IEA Ras protein signal transduction
GO:0008104 IEA protein localization
GO:0008202 IEA steroid metabolic process
GO:0008203 IEA cholesterol metabolic process
GO:0008285 IEA negative regulation of cell proliferation
GO:0008762 IEA UDP-N-acetylmuramate dehydrogenase activity
GO:0009725 IEA response to hormone
GO:0009888 IMP tissue development
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016125 IEA sterol metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016614 IEA oxidoreductase activity, acting on CH-OH group of donors
GO:0016628 IDA oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0019899 IPI enzyme binding
GO:0030539 IEA male genitalia development
GO:0031639 IEA plasminogen activation
GO:0042605 IPI peptide antigen binding
GO:0042987 IEA amyloid precursor protein catabolic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588 ISS skin development
GO:0044281 TAS small molecule metabolic process
GO:0050614 IEA delta24-sterol reductase activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IMP:IEA oxidation-reduction process
GO:0061024 IEA membrane organization
GO:1901214 NAS regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047973 Dhcr24-001 protein_coding Mus_musculus 0 2172

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