C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol polyphosphate-5-phosphatase, 75kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373027 INPP5B-002 ENSG00000204084 9606 - 1:37860697-37931749 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000373027
Transcript ID Adipose Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000373027 1.954±0.00 2.736±0.00 2.654±1.36 2.086±0.00 0.884±0.58 0.774±0.00 1.321±0.04 1.057±0.00 2.521±0.58 4.117±1.37 3.081±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00095Y CIL_00095Y_0001 VISTA 1:37729017-38330016
CIL_0007UI CIL_0007UI_0001 VISTA 1:37794522-38395934

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004439 IDA phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005886 TAS plasma membrane
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 IDA membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046856 IDA:IEA phosphatidylinositol dephosphorylation
GO:0046872 IEA metal ion binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0052658 IDA inositol-1,4,5-trisphosphate 5-phosphatase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000094782 Inpp5b-001 protein_coding Mus_musculus 0 2531
ENSMUST00000184454 Inpp5b-002 nonsense_mediated_decay Mus_musculus 0 1786
ENSMUST00000142446 Inpp5b-003 processed_transcript Mus_musculus 0 379
ENSMUST00000135971 Inpp5b-008 processed_transcript Mus_musculus 0 213

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