C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: corticotropin releasing hormone receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000398285 CRHR1-001 ENSG00000120088 9606 + 17:45784545-45835828 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003X6 CIL_0003X6_0001 CGP 17:45784280-45847072

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001965 IEA G-protein alpha-subunit binding
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005771 IEA multivesicular body
GO:0005802 IEA trans-Golgi network
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006955 TAS immune response
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IEA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007565 NAS female pregnancy
GO:0007567 TAS parturition
GO:0007613 IEA memory
GO:0008542 IEA visual learning
GO:0009755 IEA hormone-mediated signaling pathway
GO:0010578 IMP regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0010579 IDA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0015056 IDA corticotrophin-releasing factor receptor activity
GO:0016020 IEA membrane
GO:0016021 IDA:IEA integral component of membrane
GO:0021854 IEA hypothalamus development
GO:0030325 IEA adrenal gland development
GO:0030425 IEA dendrite
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0030855 IEA epithelial cell differentiation
GO:0031226 IDA intrinsic component of plasma membrane
GO:0031982 IEA vesicle
GO:0032403 IEA protein complex binding
GO:0032811 IEA negative regulation of epinephrine secretion
GO:0035641 IEA locomotory exploration behavior
GO:0035902 IEA response to immobilization stress
GO:0042277 IEA peptide binding
GO:0042596 IEA fear response
GO:0043025 IEA neuronal cell body
GO:0043306 IEA positive regulation of mast cell degranulation
GO:0043404 IEA corticotropin-releasing hormone receptor activity
GO:0045177 IEA apical part of cell
GO:0048148 IEA behavioral response to cocaine
GO:0048149 IEA behavioral response to ethanol
GO:0048167 IEA regulation of synaptic plasticity
GO:0048266 IEA behavioral response to pain
GO:0051424 IEA corticotropin-releasing hormone binding
GO:0051458 ISS corticotropin secretion
GO:0051602 IEA response to electrical stimulus
GO:0051867 IEA general adaptation syndrome, behavioral process
GO:0060291 IEA long-term synaptic potentiation
GO:0071376 IDA cellular response to corticotropin-releasing hormone stimulus
GO:1901215 IEA negative regulation of neuron death
GO:1901386 IDA negative regulation of voltage-gated calcium channel activity
GO:2000252 IEA negative regulation of feeding behavior
GO:2000852 ISS regulation of corticosterone secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000093925 Crhr1-001 protein_coding Mus_musculus 0 1136
ENSDART00000111751 crhr1-201 protein_coding Danio_rerio 7e-33 147
ENSDART00000156527 crhr1-001 protein_coding Danio_rerio 7e-33 147
ENSMUST00000016172 Celsr1-201 protein_coding Mus_musculus 0.0002 53

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