C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: corticotropin releasing hormone receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000093925 Crhr1-001 ENSMUSG00000018634 10090 + 11:104132855-104175523 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainColonLiverLungMuscleOvaryPlacentaTestisENSMUST00000093925
Transcript ID Adrenal Bladder Brain Colon Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093925 0.038±0.02 0.028±0.01 4.170±0.50 0.069±0.02 0.010±0.01 0.012±0.00 0.029±0.00 0.744±0.45 0.028±0.03 0.220±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003X6 CIL_0003X6_0002 CGP 11:104132855-104191163

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001965 IEA G-protein alpha-subunit binding
GO:0005515 IEA protein binding
GO:0005771 IEA multivesicular body
GO:0005802 IEA trans-Golgi network
GO:0005886 IEA plasma membrane
GO:0007188 IEA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007613 IEA memory
GO:0008542 IEA visual learning
GO:0009755 IEA hormone-mediated signaling pathway
GO:0010578 IEA regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0010579 IMP positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0015056 IMP corticotrophin-releasing factor receptor activity
GO:0021854 IEA hypothalamus development
GO:0030325 IMP adrenal gland development
GO:0030425 IEA dendrite
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0030855 IEA epithelial cell differentiation
GO:0031226 ISS intrinsic component of plasma membrane
GO:0031982 IEA vesicle
GO:0032403 IEA protein complex binding
GO:0032811 IEA negative regulation of epinephrine secretion
GO:0035641 IEA locomotory exploration behavior
GO:0035902 IEA response to immobilization stress
GO:0042277 IEA peptide binding
GO:0042596 IMP fear response
GO:0043025 IEA neuronal cell body
GO:0043306 IEA positive regulation of mast cell degranulation
GO:0043404 IEA corticotropin-releasing hormone receptor activity
GO:0045177 IEA apical part of cell
GO:0048148 IEA behavioral response to cocaine
GO:0048149 IMP behavioral response to ethanol
GO:0048167 IEA regulation of synaptic plasticity
GO:0048266 IEA behavioral response to pain
GO:0051424 IEA corticotropin-releasing hormone binding
GO:0051458 IMP corticotropin secretion
GO:0051602 IEA response to electrical stimulus
GO:0051867 IMP general adaptation syndrome, behavioral process
GO:0060291 IEA long-term synaptic potentiation
GO:0071376 IMP cellular response to corticotropin-releasing hormone stimulus
GO:1901215 IEA negative regulation of neuron death
GO:1901386 IEA negative regulation of voltage-gated calcium channel activity
GO:2000252 IEA negative regulation of feeding behavior
GO:2000852 IMP regulation of corticosterone secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000156527 crhr1-001 protein_coding Danio_rerio 0 828
ENSDART00000111751 crhr1-201 protein_coding Danio_rerio 0 822
ENST00000293493 CRHR1-201 protein_coding Homo_sapiens 0 883
ENST00000314537 CRHR1-002 protein_coding Homo_sapiens 0 1772
ENST00000339069 CRHR1-202 protein_coding Homo_sapiens 0 1280
ENST00000347197 CRHR1-005 nonsense_mediated_decay Homo_sapiens 0 1014
ENST00000352855 CRHR1-003 protein_coding Homo_sapiens 0 1376
ENST00000398285 CRHR1-001 protein_coding Homo_sapiens 0 1136
ENST00000535778 CRHR1-008 nonsense_mediated_decay Homo_sapiens 8e-20 102
ENST00000577353 CRHR1-004 protein_coding Homo_sapiens 0 1454
ENST00000580876 CRHR1-009 protein_coding Homo_sapiens 0 213
ENST00000580955 CRHR1-006 nonsense_mediated_decay Homo_sapiens 0 303
ENST00000581479 CRHR1-011 retained_intron Homo_sapiens 0 226
ENST00000582766 CRHR1-007 retained_intron Homo_sapiens 0 442
ENST00000583888 CRHR1-010 nonsense_mediated_decay Homo_sapiens 0 473
ENST00000611599 CRHR1-210 protein_coding Homo_sapiens 0 1275
ENST00000613260 CRHR1-211 protein_coding Homo_sapiens 0 1131
ENST00000614143 CRHR1-212 protein_coding Homo_sapiens 0 883
ENST00000615345 CRHR1-213 protein_coding Homo_sapiens 0 1387
ENST00000616225 CRHR1-204 protein_coding Homo_sapiens 0 883
ENST00000616274 CRHR1-205 protein_coding Homo_sapiens 0 1136
ENST00000616748 CRHR1-206 protein_coding Homo_sapiens 0 1393
ENST00000617446 CRHR1-214 protein_coding Homo_sapiens 0 1279
ENST00000617905 CRHR1-207 protein_coding Homo_sapiens 0 1772
ENST00000618144 CRHR1-208 protein_coding Homo_sapiens 0 1284
ENST00000618382 CRHR1-215 protein_coding Homo_sapiens 0 1766
ENST00000619154 CRHR1-203 protein_coding Homo_sapiens 0 1284
ENST00000621969 CRHR1-209 protein_coding Homo_sapiens 0 1280

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