C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000419142 TAP2-001 ENSG00000237599 9606 - CHR_HSCHR6_MHC_MCF_CTG1:32858902-32872254 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002481 IBA antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 IBA antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 IMP antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 IBA positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0005215 IDA transporter activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0015197 IGI peptide transporter activity
GO:0015433 IMP peptide antigen-transporting ATPase activity
GO:0015440 IEA peptide-transporting ATPase activity
GO:0016020 IDA membrane
GO:0016021 IDA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0019060 IMP intracellular transport of viral protein in host cell
GO:0019885 IMP:IEA antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 IPI MHC class Ib protein binding
GO:0030176 IDA:IEA integral component of endoplasmic reticulum membrane
GO:0042287 IEA MHC protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042626 IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042825 IDA:IEA TAP complex
GO:0046967 IMP cytosol to ER transport
GO:0046968 IMP peptide antigen transport
GO:0046978 IPI TAP1 binding
GO:0046980 ISS tapasin binding
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025197 Tap2-001 protein_coding Mus_musculus 0 1572
ENSMUST00000127543 Tap2-002 retained_intron Mus_musculus 0 665

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