C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025197 Tap2-001 ENSMUSG00000024339 10090 + 17:34203527-34216321 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025197
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025197 5.002±0.89 7.791±2.13 4.697±0.00 0.271±0.19 12.260±0.53 4.296±0.69 1.876±0.34 2.264±0.09 1.319±0.44 6.900±1.19 0.829±0.21 4.390±0.40 1.232±0.21 0.203±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001916 IDA positive regulation of T cell mediated cytotoxicity
GO:0002237 IMP response to molecule of bacterial origin
GO:0002481 IMP antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 IDA antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 IDA antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 IBA positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0006200 IEA ATP catabolic process
GO:0015031 IEA protein transport
GO:0015197 IEA peptide transporter activity
GO:0015833 IEA peptide transport
GO:0016021 IBA integral component of membrane
GO:0042626 IBA ATPase activity, coupled to transmembrane movement of substances
GO:0046978 IPI TAP1 binding
GO:0046980 ISS tapasin binding
GO:0055085 IBA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000374897 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000374899 TAP2-002 protein_coding Homo_sapiens 0 1489
ENST00000383118 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000383119 TAP2-002 protein_coding Homo_sapiens 0 1489
ENST00000383239 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000383240 TAP2-002 protein_coding Homo_sapiens 0 1489
ENST00000414145 TAP2-002 protein_coding Homo_sapiens 0 1483
ENST00000419142 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000426977 TAP2-002 protein_coding Homo_sapiens 0 1495
ENST00000439425 TAP2-002 protein_coding Homo_sapiens 0 1495
ENST00000443713 TAP2-001 protein_coding Homo_sapiens 0 1567
ENST00000445986 TAP2-002 protein_coding Homo_sapiens 0 1489
ENST00000451907 TAP2-002 protein_coding Homo_sapiens 0 1495
ENST00000452371 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000452392 TAP2-001 protein_coding Homo_sapiens 0 1489
ENST00000455842 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000457634 TAP2-001 protein_coding Homo_sapiens 0 1572
ENST00000462883 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000464100 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000481574 TAP2-004 retained_intron Homo_sapiens 0 436
ENST00000485043 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000485516 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000486525 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000495722 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000495854 TAP2-004 retained_intron Homo_sapiens 0 442
ENST00000612574 TAP2-203 protein_coding Homo_sapiens 0 1563
ENST00000613095 TAP2-202 protein_coding Homo_sapiens 0 1563
ENST00000619283 TAP2-205 protein_coding Homo_sapiens 0 1563
ENST00000620123 TAP2-201 protein_coding Homo_sapiens 0 1563
ENST00000620674 TAP2-204 protein_coding Homo_sapiens 0 1557

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