C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glial cell derived neurotrophic factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000427982 GDNF-004 ENSG00000168621 9606 - 5:37815651-37835827 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001656 ISS metanephros development
GO:0001657 IEA ureteric bud development
GO:0001658 ISS branching involved in ureteric bud morphogenesis
GO:0001755 IDA neural crest cell migration
GO:0001759 IEA organ induction
GO:0001941 IEA postsynaptic membrane organization
GO:0003337 IEA mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0005102 TAS receptor binding
GO:0005576 IDA extracellular region
GO:0007165 TAS signal transduction
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0007422 IEA peripheral nervous system development
GO:0008083 IEA growth factor activity
GO:0008344 TAS adult locomotory behavior
GO:0021784 ISS postganglionic parasympathetic nervous system development
GO:0030432 ISS peristalsis
GO:0031175 IDA neuron projection development
GO:0032770 IDA positive regulation of monooxygenase activity
GO:0033603 TAS positive regulation of dopamine secretion
GO:0042803 IDA protein homodimerization activity
GO:0043066 TAS negative regulation of apoptotic process
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048255 IDA mRNA stabilization
GO:0048484 ISS enteric nervous system development
GO:0048485 ISS sympathetic nervous system development
GO:0051584 IDA regulation of dopamine uptake involved in synaptic transmission
GO:0060676 IEA ureteric bud formation
GO:0060688 ISS regulation of morphogenesis of a branching structure
GO:0072107 IDA positive regulation of ureteric bud formation
GO:0072108 IEA positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0090190 IDA positive regulation of branching involved in ureteric bud morphogenesis
GO:2001240 IDA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022744 Gdnf-201 protein_coding Mus_musculus 0 859

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