C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: POU class 5 homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000433063 POU5F1-001 ENSG00000235068 9606 - CHR_HSCHR6_MHC_MCF_CTG1:31242859-31249234 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000981 ISS sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001714 IDA endodermal cell fate specification
GO:0001824 ISS blastocyst development
GO:0003130 IMP BMP signaling pathway involved in heart induction
GO:0003677 IDA:IEA DNA binding
GO:0003700 IEA:IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IC nucleus
GO:0005654 IDA nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006355 IEA:IDA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0009611 IEP response to wounding
GO:0009653 TAS anatomical structure morphogenesis
GO:0009786 ISS regulation of asymmetric cell division
GO:0010468 IMP regulation of gene expression
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035019 IMP somatic stem cell maintenance
GO:0035198 IDA miRNA binding
GO:0035413 IDA positive regulation of catenin import into nucleus
GO:0042789 ISS mRNA transcription from RNA polymerase II promoter
GO:0043565 IEA:IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060391 IDA positive regulation of SMAD protein import into nucleus
GO:0060795 IMP cell fate commitment involved in formation of primary germ layer
GO:0060913 IDA cardiac cell fate determination
GO:0060965 IMP negative regulation of gene silencing by miRNA
GO:0090081 IMP regulation of heart induction by regulation of canonical Wnt signaling pathway
GO:0090308 IDA regulation of methylation-dependent chromatin silencing

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025271 Pou5f1-001 protein_coding Mus_musculus 0 972

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