C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: POU domain, class 5, transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025271 Pou5f1-001 ENSMUSG00000024406 10090 + 17:35506018-35510772 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverOvaryPlacentaTestisENSMUST00000025271
Transcript ID Brain Heart Liver Ovary Placenta Testis
ENSMUST00000025271 0.011±0.00 0.022±0.00 0.008±0.00 1.704±0.48 0.021±0.01 3.473±1.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090O CIL_00090O_0002 VISTA 17:35419853-36021785

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001105 IEA RNA polymerase II transcription coactivator activity
GO:0001710 IDA mesodermal cell fate commitment
GO:0001711 IDA endodermal cell fate commitment
GO:0001712 IDA ectodermal cell fate commitment
GO:0001714 ISO endodermal cell fate specification
GO:0001824 IEP blastocyst development
GO:0001829 IGI trophectodermal cell differentiation
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0009786 IEP regulation of asymmetric cell division
GO:0010033 IDA response to organic substance
GO:0017053 IDA transcriptional repressor complex
GO:0019827 IMP stem cell maintenance
GO:0030718 IMP germ-line stem cell maintenance
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032526 IDA response to retinoic acid
GO:0034097 IEA response to cytokine
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045165 IMP cell fate commitment
GO:0045596 IGI negative regulation of cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI:IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045955 IDA negative regulation of calcium ion-dependent exocytosis
GO:0046982 IDA protein heterodimerization activity
GO:0048863 IDA stem cell differentiation
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0070974 IEA POU domain binding
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000259915 POU5F1-001 protein_coding Homo_sapiens 0 977
ENST00000376243 POU5F1-002 protein_coding Homo_sapiens 0 688
ENST00000383524 POU5F1-001 protein_coding Homo_sapiens 0 972
ENST00000412166 POU5F1-002 protein_coding Homo_sapiens 0 688
ENST00000419095 POU5F1-002 protein_coding Homo_sapiens 0 688
ENST00000428824 POU5F1P3-001 processed_pseudogene Homo_sapiens 0 891
ENST00000429314 POU5F1-002 protein_coding Homo_sapiens 0 688
ENST00000429603 POU5F1-001 protein_coding Homo_sapiens 0 972
ENST00000433063 POU5F1-001 protein_coding Homo_sapiens 0 972
ENST00000433348 POU5F1-002 protein_coding Homo_sapiens 0 688
ENST00000434616 POU5F1-001 protein_coding Homo_sapiens 0 972
ENST00000437747 POU5F1-001 protein_coding Homo_sapiens 0 972
ENST00000441888 POU5F1-004 protein_coding Homo_sapiens 0 693
ENST00000445059 POU5F1P5-001 processed_pseudogene Homo_sapiens 0 392
ENST00000451077 POU5F1-002 protein_coding Homo_sapiens 0 688
ENST00000454714 POU5F1-001 protein_coding Homo_sapiens 0 972
ENST00000463773 POU5F1-004 processed_transcript Homo_sapiens 0 394
ENST00000465342 POU5F1B-001 protein_coding Homo_sapiens 0 905
ENST00000471529 POU5F1-002 protein_coding Homo_sapiens 0 693
ENST00000483880 POU5F1-004 processed_transcript Homo_sapiens 0 394
ENST00000495227 POU5F1-004 processed_transcript Homo_sapiens 0 394
ENST00000496130 POU5F1-004 processed_transcript Homo_sapiens 0 394
ENST00000497087 POU5F1-004 processed_transcript Homo_sapiens 0 394
ENST00000497367 POU5F1-004 processed_transcript Homo_sapiens 0 394
ENST00000512818 POU5F1-006 protein_coding Homo_sapiens 0 693
ENST00000513407 POU5F1-005 protein_coding Homo_sapiens 0 551
ENST00000547234 POU5F1-206 protein_coding Homo_sapiens 0 913
ENST00000548682 POU5F1-207 protein_coding Homo_sapiens 0 913
ENST00000548685 POU5F1-208 protein_coding Homo_sapiens 0 913
ENST00000549294 POU5F1-205 protein_coding Homo_sapiens 0 913
ENST00000550521 POU5F1-204 protein_coding Homo_sapiens 0 913
ENST00000550572 POU5F1-203 protein_coding Homo_sapiens 0 913
ENST00000606567 POU5F1-007 protein_coding Homo_sapiens 0 693
ENST00000619340 POU5F1-201 protein_coding Homo_sapiens 0 918
ENST00000620031 POU5F1-202 protein_coding Homo_sapiens 0 693

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