C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000440650 PIK3CG-001 ENSG00000105851 9606 + 7:106865278-106905821 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000440650
Transcript ID Bladder Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000440650 0.110±0.00 0.229±0.09 0.128±0.02 0.421±0.00 0.556±0.00 0.070±0.00 0.165±0.06 0.129±0.00 1.999±0.51

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001816 TAS cytokine production
GO:0002250 TAS adaptive immune response
GO:0002407 TAS dendritic cell chemotaxis
GO:0002679 TAS respiratory burst involved in defense response
GO:0004672 TAS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IBA plasma membrane
GO:0005944 IDA phosphatidylinositol 3-kinase complex, class IB
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006897 IEA endocytosis
GO:0006954 TAS inflammatory response
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0010818 TAS T cell chemotaxis
GO:0014065 IDA phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0016303 IBA 1-phosphatidylinositol-3-kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030168 TAS platelet activation
GO:0030593 TAS neutrophil chemotaxis
GO:0033628 TAS regulation of cell adhesion mediated by integrin
GO:0035004 TAS phosphatidylinositol 3-kinase activity
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035747 TAS natural killer cell chemotaxis
GO:0042098 TAS T cell proliferation
GO:0042110 TAS T cell activation
GO:0042629 TAS mast cell granule
GO:0043303 TAS mast cell degranulation
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046875 IPI ephrin receptor binding
GO:0046934 IBA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0055118 TAS negative regulation of cardiac muscle contraction
GO:0070527 TAS platelet aggregation
GO:0072672 TAS neutrophil extravasation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000053215 Pik3cg-001 protein_coding Mus_musculus 0 3808
ENSMUST00000156904 Pik3cg-003 nonsense_mediated_decay Mus_musculus 0 3808
ENSMUST00000085469 Pik3cg-002 protein_coding Mus_musculus 0 3807
ENSDART00000009076 pik3cg-001 protein_coding Danio_rerio 0 558
ENSMUST00000126814 Pik3cg-004 retained_intron Mus_musculus 0 267

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