C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: diablo, IAP-binding mitochondrial protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000443649 DIABLO-003 ENSG00000184047 9606 - 12:122207669-122227534 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartOvaryENST00000443649
Transcript ID Colon Heart Ovary
ENST00000443649 2.451±0.00 1.698±0.00 12.954±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA:IEA mitochondrion
GO:0005758 TAS mitochondrial intermembrane space
GO:0005829 TAS cytosol
GO:0006915 TAS:IEA apoptotic process
GO:0006919 TAS:IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008625 TAS extrinsic apoptotic signaling pathway via death domain receptors
GO:0008631 IEA intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0008635 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0009898 ISS cytoplasmic side of plasma membrane
GO:0035631 ISS CD40 receptor complex
GO:0043065 TAS positive regulation of apoptotic process
GO:0051402 IEA neuron apoptotic process
GO:0097193 TAS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111587 Diablo-001 protein_coding Mus_musculus 0 776
ENSMUST00000125652 Diablo-002 nonsense_mediated_decay Mus_musculus 0 741
ENSMUST00000031385 Diablo-005 protein_coding Mus_musculus 0 531
ENSMUST00000111586 Diablo-006 protein_coding Mus_musculus 0 529
ENSMUST00000145152 Diablo-003 retained_intron Mus_musculus 0 424
ENSMUST00000139398 Diablo-004 retained_intron Mus_musculus 0 424
ENSMUST00000125047 Diablo-007 retained_intron Mus_musculus 0 411
ENSMUST00000149334 Diablo-008 retained_intron Mus_musculus 8.00001e-42 176

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