C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitofusin 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000444836 MFN2-201 ENSG00000116688 9606 + 1:11980181-12013514 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000444836
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000444836 4.172±0.00 12.741±0.00 6.725±3.85 5.142±0.00 10.885±0.00 15.675±0.00 8.002±5.50 10.260±0.00 9.008±0.00 31.211±0.00 18.008±15.49 11.921±8.29 6.431±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0001 VISTA 1:11580820-12184055
CIL_00022Z CIL_00022Z_0002 CGP 1:11934205-12013514

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005739 IDA mitochondrion
GO:0005741 TAS:IEA mitochondrial outer membrane
GO:0005829 ISS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006626 IDA protein targeting to mitochondrion
GO:0006914 IEA autophagy
GO:0006915 IEA apoptotic process
GO:0006986 IEA response to unfolded protein
GO:0007006 IDA mitochondrial membrane organization
GO:0007596 TAS blood coagulation
GO:0008053 ISS:IEA mitochondrial fusion
GO:0016021 IEA integral component of membrane
GO:0031306 ISS intrinsic component of mitochondrial outer membrane
GO:0031625 IPI ubiquitin protein ligase binding
GO:0034497 IDA protein localization to pre-autophagosomal structure
GO:0046580 IDA negative regulation of Ras protein signal transduction
GO:0048662 IEA:ISS negative regulation of smooth muscle cell proliferation
GO:0051646 IDA mitochondrion localization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105715 Mfn2-004 protein_coding Mus_musculus 0 2957
ENSMUST00000030884 Mfn2-002 protein_coding Mus_musculus 0 2957
ENSMUST00000105716 Mfn2-001 protein_coding Mus_musculus 0 2957
ENSMUST00000105714 Mfn2-003 protein_coding Mus_musculus 0 2230
ENSMUST00000134172 Mfn2-007 protein_coding Mus_musculus 0 769
ENSMUST00000124646 Mfn2-008 processed_transcript Mus_musculus 0 429

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