C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BCL2-like 11 (apoptosis facilitator)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000452231 BCL2L11-009 ENSG00000153094 9606 + 2:111123746-111164231 nonsense_mediated_decay

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047S CIL_00047S_0001 CGP 2:110732573-111168447

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0005874 IDA microtubule
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008017 IDA microtubule binding
GO:0008630 IDA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0043065 IMP positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0090200 IMP positive regulation of release of cytochrome c from mitochondria
GO:0097140 IDA BIM-BCL-xl complex
GO:0097141 IDA BIM-BCL-2 complex
GO:0097190 TAS apoptotic signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2000271 IDA positive regulation of fibroblast apoptotic process
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019281 Bcl2l11-201 protein_coding Mus_musculus 0 246
ENSMUST00000103211 Bcl2l11-006 protein_coding Mus_musculus 0 246
ENSMUST00000103210 Bcl2l11-005 protein_coding Mus_musculus 0 191
ENSMUST00000129206 Bcl2l11-004 processed_transcript Mus_musculus 0 191
ENSMUST00000089634 Bcl2l11-003 protein_coding Mus_musculus 0 191
ENSMUST00000146023 Bcl2l11-002 processed_transcript Mus_musculus 0 191
ENSMUST00000110341 Bcl2l11-001 protein_coding Mus_musculus 0 191
ENSMUST00000132201 Bcl2l11-007 processed_transcript Mus_musculus 1e-39 167

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